Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Q36744611)

16 August 2017

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title

Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (English)

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16 August 2017

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Pascal Lapierre

1

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PubMed ID

17320796

16 August 2017

Kathie Béland

series ordinal

2

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PubMed ID

17320796

16 August 2017

Fernando Alvarez

series ordinal

3

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16 August 2017

1 March 2007

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16 August 2017

Translational Research

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16 August 2017

149

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16 August 2017

3

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16 August 2017

107-113

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Meeting report: International Autoimmune Hepatitis Group

16 August 2017

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

7 January 2021

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Chronic active hepatitis associated with antiliver/kidney microsome antibody type 1: a second type of "autoimmune" hepatitis

7 January 2021

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Liver disease associated with anti-liver-kidney microsome antibody in children

7 January 2021

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Autoimmune hepatitis associated with anti-actin antibodies in children and adolescents

7 January 2021

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Autoimmune hepatitis in childhood: a 20-year experience.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Linkage disequilibrium between HLA class II region and autoimmune hepatitis in pediatric patients.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Identification of the main epitope on human cytochrome P450 IID6 recognized by anti-liver kidney microsome antibody

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Identification and analysis of cytochrome P450IID6 antigenic sites recognized by anti-liver-kidney microsome type-1 antibodies (LKM1)

7 January 2021

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Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Antibody to liver cytosol (anti-LC1) in patients with autoimmune chronic active hepatitis type 2

7 January 2021

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Characterization of the liver cytosol antigen type 1 reacting with autoantibodies in chronic active hepatitis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Formiminotransferase cyclodeaminase is an organ-specific autoantigen recognized by sera of patients with autoimmune hepatitis

7 January 2021

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Autoreactive CD4+ LKM-specific and anticlonotypic T-cell responses in LKM-1 antibody-positive autoimmune hepatitis

7 January 2021

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Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

7 January 2021

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LKM1 autoantibodies in chronic hepatitis C infection: a case of molecular mimicry?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

DNA vaccination breaks tolerance for a neo-self antigen in liver: a transgenic murine model of autoimmune hepatitis

7 January 2021

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Using transgenic mouse models to dissect the pathogenesis of virus-induced autoimmune disorders of the islets of Langerhans and the central nervous system

7 January 2021

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Characterization of the B cell response of patients with anti-liver cytosol autoantibodies in type 2 autoimmune hepatitis

7 January 2021

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A murine model of type 2 autoimmune hepatitis: Xenoimmunization with human antigens

7 January 2021

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Type 2 autoimmune hepatitis murine model: the influence of genetic background in disease development

7 January 2021

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Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

7 January 2021

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Kupffer cells required for high affinity peptide-induced deletion, not retention, of activated CD8+ T cells by mouse liver

7 January 2021

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Intrahepatic immunity: a tale of two sites?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Passive and active mechanisms trap activated CD8+ T cells in the liver.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice

7 January 2021

1 reference

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Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1

7 January 2021

1 reference

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Lymphocyte traffic through sinusoidal endothelial cells is regulated by hepatocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Chemokines in autoimmune disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis.

7 January 2021

1 reference

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CXCR3 and CCR5 ligands in rheumatoid arthritis synovium

7 January 2021

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Persistent induction of the chemokine receptor CXCR4 by TGF-beta 1 on synovial T cells contributes to their accumulation within the rheumatoid synovium.

7 January 2021

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A Common Stromal Cell-Derived Factor-1 Chemokine Gene Variant is Associated With the Early Onset of Type 1 Diabetes

7 January 2021

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Chemokine expression and leucocyte infiltration in Sjögren's syndrome

7 January 2021

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Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies

7 January 2021

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Expression of CCL21 and 5'-Nase on pancreatic lymphatics in nonobese diabetic mice

7 January 2021

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Critical roles of CXC chemokine ligand 16/scavenger receptor that binds phosphatidylserine and oxidized lipoprotein in the pathogenesis of both acute and adoptive transfer experimental autoimmune encephalomyelitis

7 January 2021

1 reference

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Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

7 January 2021

1 reference

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Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions

7 January 2021

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Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue

7 January 2021

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SERUM LEVELS OF IFN-INDUCIBLE PROTEIN-10 RELATING TO THE ACTIVITY OF SYSTEMIC LUPUS ERYTHEMATOSUS

7 January 2021

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Chemokine regulation of naïve T cell traffic in health and disease

7 January 2021

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Hepatic expression of secondary lymphoid chemokine (CCL21) promotes the development of portal-associated lymphoid tissue in chronic inflammatory liver disease

7 January 2021

1 reference

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Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C.

7 January 2021

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Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus

7 January 2021

1 reference

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CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver

7 January 2021

1 reference

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Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells.

7 January 2021

1 reference

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CCR5 deficiency exacerbates T-cell-mediated hepatitis in mice

7 January 2021

1 reference

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Role for CXCR6 in recruitment of activated CD8+ lymphocytes to inflamed liver.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2006.11.010

7 January 2021

Chemokines and disease

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Two CD95 (APO-1/Fas) signaling pathways

7 January 2021

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Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

7 January 2021

1 reference

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Induction of murine hepatocyte death by membrane-bound CD95 (Fas/APO-1)-ligand: characterization of an in vitro system

7 January 2021

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Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice

7 January 2021

1 reference

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Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.

7 January 2021

1 reference

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Fas and TNFR1, but not cytolytic granule-dependent mechanisms, mediate clearance of murine liver adenoviral infection

7 January 2021

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NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis.

7 January 2021

1 reference

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Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8+ T-cell activation by bone marrow–derived cells

7 January 2021

1 reference

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10.1016/J.TRSL.2006.11.010

7 January 2021

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17320796