Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated) (Q36749051)

16 August 2017

6 references

22 June 2019

4 August 2019

18 November 2019

27 November 2019

21 December 2019

1 February 2021

Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated) (English)

1 reference

Protein C, inactivator of coagulation factors Va and VIIIa

16 August 2017

0 references

1 reference

1 February 2021

1 reference

4 August 2019

1 reference

18 November 2019

1 reference

27 November 2019

1 reference

21 December 2019

1 reference

1 February 2021

1 reference

5

1 reference

16 August 2017

Andrew F Shorr

1

1 reference

16 August 2017

David R Nelson

2

1 reference

16 August 2017

Duncan L A Wyncoll

3

1 reference

16 August 2017

Konrad Reinhart

4

1 reference

16 August 2017

George Matthew Vail

6

1 reference

16 August 2017

Jonathan Janes

7

1 reference

16 August 2017

language of work or name

1 reference

4 April 2008

7 references

16 August 2017

22 June 2019

4 August 2019

18 November 2019

27 November 2019

21 December 2019

1 February 2021

7 references

16 August 2017

22 June 2019

4 August 2019

18 November 2019

27 November 2019

21 December 2019

1 February 2021

12

1 reference

16 August 2017

2

1 reference

16 August 2017

R45

1 reference

Creative Commons Attribution 2.0 Generic

16 August 2017

6 references

22 June 2019

4 August 2019

18 November 2019

27 November 2019

21 December 2019

on focus list of Wikimedia project

1 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

The protein C pathway: implications for the design of the RESPOND study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Current diagnosis of venous thromboembolism in primary care: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

The cytoprotective protein C pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Biomarkers of cardiovascular disease: molecular basis and practical considerations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

B-type natriuretic peptide in heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

The promise of protein C.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

B-type natriuretic peptide as a biomarker beyond heart failure: speculations and opportunities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Efficacy and safety of recombinant human activated protein C for severe sepsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Epidemic meningococcemia and purpura fulminans with induced protein C deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Relation between cytokines and routine laboratory data in children with septic shock and purpura.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Liver dysfunction in critical illness

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Protein S and C alterations in acutely ill patients

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Activated protein C reduces tissue hypoxia, inflammation, and apoptosis in traumatized skeletal muscle during endotoxemia.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Gene expression profiling of inflamed human endothelial cells and influence of activated protein C.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Severe protein C deficiency predicts early death in severe sepsis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

A method to assess the proportion of treatment effect explained by a surrogate endpoint

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Low levels of protein C are associated with poor outcome in severe sepsis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Coagulation activation and tissue necrosis in meningococcal septic shock: severely reduced protein C levels predict a high mortality.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Protein C, protein S and C4b-binding protein in neonatal severe infection and septic shock

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447591

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis

20 October 2018

1 reference

12 December 2020

D-dimer levels correlate with mortality in patients with acute pulmonary embolism: Findings from the RIETE registry

1 reference

12 December 2020

Protein C, protein S and C4b-binding protein in severe infection and septic shock

1 reference

12 December 2020

Protein C and S deficiency in severe infectious purpura of children: a collaborative study of 40 cases

1 reference

12 December 2020

Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment*

1 reference

12 December 2020

Pathophysiology of sepsis

1 reference

12 December 2020

Time course of hemostatic abnormalities in sepsis and its relation to outcome.

1 reference

12 December 2020

Statistical validation of intermediate endpoints for chronic diseases

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC6854

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

18394162

1 reference