Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy (Q36752354)

16 August 2017

Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy (English)

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16 August 2017

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5

Judy H Cho

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16 August 2017

Jing Wang

1

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16 August 2017

Robert A Anders

2

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16 August 2017

Qiang Wu

3

1 reference

16 August 2017

Dacheng Peng

4

1 reference

16 August 2017

Yonglian Sun

6

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16 August 2017

Reda Karaliukas

7

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16 August 2017

Hyung-Sik Kang

8

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16 August 2017

Jerrold R Turner

9

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16 August 2017

Yang-Xin Fu

10

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16 August 2017

language of work or name

English

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publication date

1 March 2004

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Journal of Clinical Investigation

16 August 2017

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16 August 2017

113

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16 August 2017

6

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16 August 2017

826-835

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Lymphotoxin/light, lymphoid microenvironments and autoimmune disease

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation for J chain mRNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Systemic and mucosal IgA responses to systemic antigen challenge in IgA nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Increased dimeric IgA-producing B cells in tonsils in IgA nephropathy determined by in situ hybridization for J chain mRNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Altered hepatic transport of immunoglobulin A in mice lacking the J chain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

The syndrome of IgA nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Transport models for secretory IgA and secretory IgM

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Composition of IgA-containing circulating immune complexes in IgA nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

IgA nephropathy and mucosal immune system.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Immunoregulatory factors in the pathogenesis of IgA nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

The origin and antigen-dependent distribution of IgA-containing cells in the intestine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Experimental IgA nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Requirements for B7-CD28 costimulation in mucosal IgA responses: paradoxes observed in CTLA4-H gamma 1 transgenic mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Mesenteric lymph as a major source of serum IgA in guinea pigs and rats

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

[Intercapillary deposits of IgA-IgG]

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin-specific protective immunity despite normal gut mucosal IgA differentiation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=362120

Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice

4 December 2018

1 reference

12 December 2020

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

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12 December 2020

Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production

1 reference

12 December 2020

Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA

1 reference

12 December 2020

Evidence for a specific IgA receptor in rat and human mesangial cells

1 reference

12 December 2020

B and T cell abnormalities in patients with primary IgA nephropathy

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12 December 2020

Impaired mucosal immune responses in interleukin 4-targeted mice

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12 December 2020

Immunologic studies in IgA nephropathy

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12 December 2020

The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function

1 reference

12 December 2020

Immunoglobulin A glomerular nephropathy associated with inflammatory colitis. Apropos of 2 cases

1 reference

12 December 2020

The pathogenic role of immunoglobulin A polymers in immunoglobulin A nephropathy

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12 December 2020

Recurrent immunoglobulin A nephropathy after renal transplantation: a significant contributor to graft loss

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12 December 2020

Yersinia enterocolitica and glomerulonephritis

1 reference

12 December 2020

Protection against cholera toxin after oral immunization is thymus-dependent and associated with intestinal production of neutralizing IgA antitoxin

1 reference

12 December 2020

Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction

1 reference

12 December 2020

Idiopathic IgA nephropathy

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI20096

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16 August 2017

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16 August 2017

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