BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss (Q36759676)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23438604%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss (English)

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24 February 2020

1

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24 February 2020

Yong-Gang Yao

series ordinal

3

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24 February 2020

author name string

Xinying Zhuang

series ordinal

2

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24 February 2020

Rugang Zhang

series ordinal

4

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24 February 2020

language of work or name

English

0 references

publication date

25 February 2013

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Molecular and Cellular Biology

24 February 2020

published in

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24 February 2020

volume

33

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24 February 2020

issue

9

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24 February 2020

page(s)

1819-1829

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Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

24 February 2020

cites work

1 reference

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Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.

29 September 2017

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Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells

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Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

29 September 2017

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SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity

29 September 2017

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The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

29 September 2017

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SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

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Molecular dissection of formation of senescence-associated heterochromatin foci

29 September 2017

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Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

29 September 2017

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

29 September 2017

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

29 September 2017

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The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

29 September 2017

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

29 September 2017

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ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

29 September 2017

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

29 September 2017

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The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway

29 September 2017

1 reference

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Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

29 September 2017

1 reference

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BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.

29 September 2017

1 reference

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Role for BRG1 in cell cycle control and tumor suppression

29 September 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

29 September 2017

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Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

29 September 2017

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Cyclin D-dependent kinases, INK4 inhibitors and cancer

29 September 2017

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BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

29 September 2017

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Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

29 September 2017

1 reference

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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

29 September 2017

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In search of the tumour-suppressor functions of BRCA1 and BRCA2

29 September 2017

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

29 September 2017

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

29 September 2017

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RB and hbrm cooperate to repress the activation functions of E2F1

29 September 2017

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Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

29 September 2017

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

29 September 2017

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

29 September 2017

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Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells

29 September 2017

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Brg1 chromatin remodeling factor is involved in cell growth arrest, apoptosis and senescence of rat mesenchymal stem cells.

29 September 2017

1 reference

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Characterization of mammary tumors from Brg1 heterozygous mice.

5 September 2018

1 reference

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HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624184

Oncogene-induced senescence as an initial barrier in lymphoma development

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624184

5 September 2018

Identifiers

DOI

10.1128/MCB.01744-12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23438604%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

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24 February 2020

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