Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis (Q36760245)

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24 February 2020

title

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis (English)

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24 February 2020

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1

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24 February 2020

Daniel Hargbøl Madsen

6

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24 February 2020

Agnes Noel

10

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24 February 2020

Lars Henning Engelholm

12

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24 February 2020

Niels Behrendt

13

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24 February 2020

author name string

Astrid Porse

2

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24 February 2020

Charlotte Erpicum

3

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24 February 2020

Ludovic Maertens

4

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24 February 2020

Henrik J Jürgensen

5

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24 February 2020

Maria C Melander

7

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24 February 2020

Henrik Gårdsvoll

8

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24 February 2020

Gunilla Høyer-Hansen

9

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24 February 2020

Kenn Holmbeck

11

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24 February 2020

language of work or name

English

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publication date

14 February 2013

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Journal of Biological Chemistry

24 February 2020

published in

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24 February 2020

volume

288

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24 February 2020

issue

15

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24 February 2020

page(s)

10195-10204

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Mutation of membrane type-1 metalloproteinase, MT1-MMP, causes the multicentric osteolysis and arthritis disease Winchester syndrome

24 February 2020

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29 September 2017

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Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

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MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D.

29 September 2017

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29 September 2017

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Recombinant interferon-gamma secreted by Chinese hamster ovary-320 cells cultivated in suspension in protein-free media is protected against extracellular proteolysis by the expression of natural protease inhibitors and by the addition of plant prot

29 September 2017

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Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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28 June 2018

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Modeling lymphangiogenesis in a three-dimensional culture system.

5 September 2018

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Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.

5 September 2018

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Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth

5 September 2018

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A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism

5 September 2018

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Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

5 September 2018

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Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization

5 September 2018

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Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

5 September 2018

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Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas

5 September 2018

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12 December 2020

Active immunogene therapy of cancer with vaccine on the basis of chicken homologous matrix metalloproteinase-2

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12 December 2020

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

1 reference

12 December 2020

MT-MMP expression and localisation in human lung and breast cancers

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12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

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12 December 2020

Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis

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12 December 2020

Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase

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12 December 2020

Different mechanisms are involved in the antibody mediated inhibition of ligand binding to the urokinase receptor: a study based on biosensor technology

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MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

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12 December 2020

Identifiers

DOI

10.1074/JBC.M112.447169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23413031%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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24 February 2020

PubMed publication ID

23413031

1 reference