Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats. (Q36765094)

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scientific article published on February 2016

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English	Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats.	scientific article published on February 2016

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scholarly article

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7 March 2020

Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats (English)

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7 March 2020

human subject research project

0 references

2 references

ChEBI release 2020-05-28

Paeonia obovata

1 reference

Paeonia veitchii

1 reference

Paeonia × suffruticosa

1 reference

1 reference

1 reference

[(1S,3R,5R,6R,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl 4-hydroxybenzoate

1 reference

1 reference

Paeonia anomala

1 reference

pharmacokinetics

1 reference

based on heuristic

inferred from title

Olajide Olaleye

13

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Europe PubMed Central

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7 March 2020

author name string

Chen Cheng

1

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7 March 2020

Jia-zhen Lin

2

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7 March 2020

Li Li

3

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7 March 2020

Jun-ling Yang

4

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7 March 2020

Wei-wei Jia

5

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7 March 2020

Yu-hong Huang

6

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Fei-fei Du

7

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7 March 2020

Feng-qing Wang

8

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7 March 2020

Mei-juan Li

9

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7 March 2020

Yan-fen Li

10

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7 March 2020

Fang Xu

11

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7 March 2020

Na-ting Zhang

12

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7 March 2020

Yan Sun

14

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7 March 2020

Jian Li

15

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7 March 2020

Chang-hai Sun

16

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7 March 2020

Gui-ping Zhang

17

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7 March 2020

Chuan Li

18

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publication date

1 February 2016

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7 March 2020

full work available at URL

https://www.nature.com/articles/aps2015103.pdf

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19 March 2024

https://api.unpaywall.org/v2/10.1038/aps.2015.103?email=unpaywall_01@example.com

Acta Pharmacologica Sinica

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7 March 2020

37

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7 March 2020

4

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7 March 2020

530-544

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7 March 2020

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/aps.2015.103?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Efficacy of Xuebijing for coagulopathy in patients with sepsis

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Renal tubular secretion of tanshinol: molecular mechanisms, impact on its systemic exposure, and propensity for dose-related nephrotoxicity and for renal herb-drug interactions

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29 September 2017

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29 September 2017

A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury.

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29 September 2017

Severe sepsis and septic shock

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29 September 2017

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Qi-shen-yi-qi dripping pills for the secondary prevention of myocardial infarction: a randomised clinical trial

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29 September 2017

Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration.

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29 September 2017

The profiling and identification of the absorbed constituents and metabolites of Paeoniae Radix Rubra decoction in rat plasma and urine by the HPLC-DAD-ESI-IT-TOF-MS(n) technique: a novel strategy for the systematic screening and identification of a

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29 September 2017

Protective effect of albiflorin against oxidative-stress-mediated toxicity in osteoblast-like MC3T3-E1 cells

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Identification of NF-κB Inhibitors in Xuebijing injection for sepsis treatment based on bioactivity-integrated UPLC-Q/TOF.

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29 September 2017

Pharmacokinetic properties of albiflorin and paeoniflorin after oral administration of pure compound, Radix Paeoniae alba extract and danggui-shaoyao-san extract to rats

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29 September 2017

Is danshen (Salvia miltiorrhiza) dripping pill more effective than isosorbide dinitrate in treating angina pectoris? A systematic review of randomized controlled trials

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29 September 2017

LC-MS/MS determination and pharmacokinetic study of albiflorin and paeoniflorin in rat plasma after oral administration of Radix Paeoniae Alba extract and Tang-Min-Ling-Wan

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29 September 2017

Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis

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29 September 2017

Paeoniflorin inhibits systemic inflammation and improves survival in experimental sepsis

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29 September 2017

Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry

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29 September 2017

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29 September 2017

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29 September 2017

Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi).

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28 June 2018

Confidence interval criteria for assessment of dose proportionality.

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28 June 2018

New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity.

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5 September 2018

Antioxidative and anti-inflammatory activities of paeoniflorin and oxypaeoniflora on AGEs-induced mesangial cell damage

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5 September 2018

A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure

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5 September 2018

Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells

1 reference

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5 September 2018

Paeoniflorin, a natural neuroprotective agent, modulates multiple anti-apoptotic and pro-apoptotic pathways in differentiated PC12 cells.

1 reference

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5 September 2018

Inhibitory effects of paeoniflorin on lysophosphatidylcholine-induced inflammatory factor production in human umbilical vein endothelial cells

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5 September 2018

Paeoniflorin protects against lipopolysaccharide-induced acute lung injury in mice by alleviating inflammatory cell infiltration and microvascular permeability.

1 reference

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5 September 2018

Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-α and IL-1β release and augmentation of IL-10 production.

1 reference

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5 September 2018

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5 September 2018

Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa

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5 September 2018

Protective effects of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism

1 reference

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5 September 2018

Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway

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5 September 2018

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1 reference

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5 September 2018

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1 reference

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1 reference

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5 September 2018

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1 reference

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5 September 2018

Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the determination of paeoniflorin in rat brain and its application to pharmacokinetic study

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5 September 2018

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5 September 2018

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1 reference

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5 September 2018

A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats

1 reference

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5 September 2018

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1 reference

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5 September 2018

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5 September 2018

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https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

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Physiological parameters in laboratory animals and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

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inferred from PubMed ID database lookup

Systemic exposure to and disposition of catechols derived from Salvia miltiorrhiza roots (Danshen) after intravenous dosing DanHong injection in human subjects, rats, and dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

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Intestinal absorption and presystemic elimination of various chemical constituents present in GBE50 extract, a standardized extract of Ginkgo biloba leaves

1 reference

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inferred from PubMed ID database lookup

Absorption and excretion of paeoniflorin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic conversion from co-existing ingredient leading to significant systemic exposure of Z-butylidenephthalide, a minor ingredient in Chuanxiong Rhizoma in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of paeoniflorin and related compounds by human intestinal bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

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inferred from PubMed ID database lookup

Reprioritization of hepatic plasma protein release in trauma and sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

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In-vivo assessment of extrahepatic metabolism of paeoniflorin in rats: relevance to intestinal floral metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/26838074

12 December 2020

based on heuristic

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10.1038/APS.2015.103

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Europe PubMed Central

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7 March 2020

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https://api.fatcat.wiki/v0/release/lmuwfdyekzevvn4yul6abwpri4

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7 March 2020

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