Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes. (Q36768015)

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scientific article published on 17 December 2015

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English	Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.	scientific article published on 17 December 2015

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2 March 2020

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes (English)

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2 March 2020

passive immunization

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based on heuristic

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spinocerebellar ataxia type 1

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based on heuristic

inferred from title

Maxime Rousseaux

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2 March 2020

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2 March 2020

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Rakez Kayed

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Cristian A. Lasagna Reeves

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Cristian A Lasagna-Reeves

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Marcos J Guerrero-Munoz

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2 March 2020

Luis Vilanova-Velez

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Jeehye Park

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Lauren See

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Paymaan Jafar-Nejad

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Ronald Richman

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17 December 2015

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2 March 2020

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2 March 2020

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.

1 reference

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RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

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Trans-synaptic spread of tau pathology in vivo

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

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29 September 2017

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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29 September 2017

Nucleated conformational conversion and the replication of conformational information by a prion determinant

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29 September 2017

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

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5 September 2018

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5 September 2018

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10.7554/ELIFE.10891

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2 March 2020

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2 March 2020

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2 March 2020

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