TLR2 deletion promotes arthritis through reduction of IL-10 (Q36775416)

16 August 2017

TLR2 deletion promotes arthritis through reduction of IL-10 (English)

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16 August 2017

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Richard M Pope

6

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author name string

Qi-Quan Huang

1

1 reference

16 August 2017

Renee E Koessler

2

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16 August 2017

Robert Birkett

3

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16 August 2017

Harris Perlman

4

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16 August 2017

Lianping Xing

5

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16 August 2017

27 February 2013

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Journal of Leukocyte Biology

16 August 2017

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16 August 2017

93

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16 August 2017

5

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16 August 2017

751-759

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describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3629443/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Rac1 regulates peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway.

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Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1

29 September 2017

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29 September 2017

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p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis

29 September 2017

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ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus

29 September 2017

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Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages

29 September 2017

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IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

29 September 2017

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Collagen-induced arthritis is exacerbated in IL-10-deficient mice

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

29 September 2017

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Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

29 September 2017

1 reference

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The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production

27 June 2018

1 reference

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Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation

27 June 2018

1 reference

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Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw.

27 June 2018

1 reference

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Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws

27 June 2018

1 reference

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Combination etanercept and methotrexate provides better disease control in very early (<=4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET study

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Arthritis critically dependent on innate immune system players

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

Immunoregulatory role of interleukin 10 in rheumatoid arthritis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629443

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1189%2FJLB.0912473

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1189%2FJLB.0912473

Deficiency in TLR2 but not in TLR4 impairs dendritic cells derived IL-10 responses to schistosome antigens

21 January 2018

1 reference

12 December 2020

Fcγ receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins

1 reference

12 December 2020

Elevated interleukin-10 levels in patients with rheumatoid arthritis

1 reference

12 December 2020

IL-10 modulates formation of osteoclasts in murine hemopoietic cultures

1 reference

12 December 2020

Interleukin-10 suppresses the development of collagen type II-induced arthritis and ameliorates sustained arthritis in rats

1 reference

12 December 2020

Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction

1 reference

12 December 2020

Local inflammation as a mediator of migraine and tension-type headache: a response

1 reference

12 December 2020

Enhanced osteoclastogenesis in 4-1BB-deficient mice caused by reduced interleukin-10

1 reference

12 December 2020

Increased macrophage activation mediated through toll-like receptors in rheumatoid arthritis

1 reference

12 December 2020

Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages

1 reference

12 December 2020

IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo

1 reference

12 December 2020

IL-10-Deficient B10.Q Mice Develop More Severe Collagen-Induced Arthritis, but Are Protected from Arthritis Induced with Anti-Type II Collagen Antibodies

1 reference

12 December 2020

Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis

1 reference

12 December 2020

Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1189/JLB.0912473

1 reference

16 August 2017

1 reference

16 August 2017

1 reference