Chronic inhibition of the Na+/H+ - exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling. (Q36790227)

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scientific article published on 19 May 2008

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English	Chronic inhibition of the Na+/H+ - exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling.	scientific article published on 19 May 2008

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scholarly article

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7 January 2020

Chronic inhibition of the Na+/H+ - exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling (English)

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7 January 2020

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electrophysiology

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Arie O. Verkerk

6

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7 January 2020

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7 January 2020

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A Baartscheer

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7 January 2020

M Hardziyenka

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7 January 2020

C A Schumacher

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C N W Belterman

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7 January 2020

M M G J van Borren

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7 January 2020

J W T Fiolet

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19 May 2008

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7 January 2020

British Journal of Pharmacology

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7 January 2020

154

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7 January 2020

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7 January 2020

1266-1275

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7 January 2020

Sodium-hydrogen exchanger, cardiac overload, and myocardial hypertrophy

1 reference

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29 September 2017

Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

1 reference

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29 September 2017

Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts.

1 reference

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29 September 2017

Effects of combined inhibition of the Na+-H+ exchanger and angiotensin-converting enzyme in rats with congestive heart failure after myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

29 September 2017

Electrophysiological changes in heart failure and their relationship to arrhythmogenesis

1 reference

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29 September 2017

Inhibition and reversal of myocardial infarction-induced hypertrophy and heart failure by NHE-1 inhibition

1 reference

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29 September 2017

Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

1 reference

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29 September 2017

Genomics and the pathophysiology of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

29 September 2017

Activation of Na(+)-H+ antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system

1 reference

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29 September 2017

Cell calcium, oncogenes, and hypertrophy

1 reference

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29 September 2017

[Na+]i and the driving force of the Na+/Ca2+-exchanger in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

27 June 2018

NHE-1-dependent intracellular sodium overload in hypertrophic hereditary cardiomyopathy: prevention by NHE-1 inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Endothelin-1 stimulates the Na+/Ca2+ exchanger reverse mode through intracellular Na+ (Na+i)-dependent and Na+i-independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

SR calcium handling and calcium after-transients in a rabbit model of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Regression of cardiomyocyte hypertrophy in SHR following chronic inhibition of the Na(+)/H(+) exchanger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

SR calcium depletion following reversal of the Na+/Ca2+-exchanger in rat ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na(+)-H(+)Exchange blockers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Partial inhibition of Na+/K+-ATPase by ouabain induces the Ca2+-dependent expressions of early-response genes in cardiac myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Passive Ca buffering and SR Ca uptake in permeabilized rabbit ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483399

5 September 2018

Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NHE-1 and NBC during pseudo-ischemia/reperfusion in rabbit ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Faster protein and ribosome synthesis in thyroxine-induced hypertrophy of rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensi

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The origin of increased cytoplasmic calcium upon reversal of the Na+/Ca(2+)-exchanger in isolated rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sodium induces hypertrophy of cultured myocardial myoblasts and vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal myocyte Ca2+ homeostasis in rabbits with pacing-induced heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regression of pressure overload-induced left ventricular hypertrophy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic inhibition of na(+)/h(+)-exchanger in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early versus delayed angiotensin-converting enzyme inhibition in experimental chronic heart failure. Effects on survival, hemodynamics, and cardiovascular remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of NHE-1 to cell length shortening of normal and failing rabbit cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18493245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJP.2008.189

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7 January 2020

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Europe PubMed Central

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7 January 2020

1 reference

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7 January 2020

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