Fatty acid receptors as new therapeutic targets for diabetes (Q36804437)

16 August 2017

1 reference

title

Fatty acid receptors as new therapeutic targets for diabetes (English)

1 reference

16 August 2017

0 references

Geetha Vani Rayasam

1

1 reference

16 August 2017

Vamshi Krishna Tulasi

series ordinal

2

1 reference

16 August 2017

Joseph Alex Davis

series ordinal

3

1 reference

16 August 2017

Vinay S Bansal

series ordinal

4

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 May 2007

1 reference

Expert Opinion on Therapeutic Targets

16 August 2017

1 reference

16 August 2017

11

1 reference

16 August 2017

661-671

1 reference

16 August 2017

5

1 reference

Mechanisms linking obesity to insulin resistance and type 2 diabetes

16 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

I want a new drug: G-protein-coupled receptors in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Interactions between insulin resistance and insulin secretion in the development of glucose intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Inflammation and metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Fatty acids, lipotoxicity and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The role of leukotrienes in the pathophysiology of inflammatory disorders: is there a case for revisiting leukotrienes as therapeutic targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Short-chain fatty acids: ready for prime time?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

An obesity-associated gut microbiome with increased capacity for energy harvest

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Microbial ecology: human gut microbes associated with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Progress in methodology. Improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

G protein-coupled receptors for free fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Continued discovery of ligands for G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Mouse GPR40 heterologously expressed in Xenopus oocytes is activated by short-, medium-, and long-chain fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

GPR40 gene expression in human pancreas and insulinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Role of GPR40 in fatty acid action on the beta cell line INS-1E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Fatty acid signaling in the beta-cell and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Existence of GPR40 functioning in a human breast cancer cell line, MCF-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Molecular cloning and tissue expression of a novel orphan G protein-coupled receptor from rat lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The role of gut hormones in glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The regulation of adipogenesis through GPR120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Synthesis and activity of small molecule GPR40 agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

Obesity-induced inflammatory changes in adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

The G-protein coupled receptor, GPR84 regulates IL-4 production by T lymphocytes in response to CD3 crosslinking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.5.661

10.1517/14728222.11.5.661

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference