Interleukin-6 contributes to CNS axon regeneration upon inflammatory stimulation (Q36809549)

16 August 2017

Interleukin-6 contributes to CNS axon regeneration upon inflammatory stimulation (English)

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16 August 2017

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M Leibinger

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16 August 2017

A Müller

2

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16 August 2017

P Gobrecht

3

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16 August 2017

H Diekmann

4

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16 August 2017

A Andreadaki

5

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16 August 2017

D Fischer

6

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16 August 2017

25 April 2013

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16 August 2017

Cell Death and Disease

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16 August 2017

4

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16 August 2017

e609

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3641349/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Promoting optic nerve regeneration.

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HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice

29 September 2017

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Neuromelanin is an immune stimulator for dendritic cells in vitro

29 September 2017

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Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

29 September 2017

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Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor

29 September 2017

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Facilitating axon regeneration in the injured CNS by microtubules stabilization.

29 September 2017

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Neuronal intrinsic mechanisms of axon regeneration.

29 September 2017

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PTEN/mTOR and axon regeneration.

29 September 2017

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Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects

29 September 2017

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Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

29 September 2017

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ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells

29 September 2017

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Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages

29 September 2017

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Glial inhibition of CNS axon regeneration

29 September 2017

1 reference

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Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation.

29 September 2017

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Intrinsic neuronal regulation of axon and dendrite growth.

29 September 2017

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Regeneration beyond the glial scar

29 September 2017

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

29 September 2017

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Cataractogenic lens injury prevents traumatic ganglion cell death and promotes axonal regeneration both in vivo and in culture

29 September 2017

1 reference

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

29 September 2017

1 reference

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Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling

29 September 2017

1 reference

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A method for preparing primary retinal cell cultures for evaluating the neuroprotective and neuritogenic effect of factors on axotomized mature CNS neurons.

27 June 2018

1 reference

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Ciliary neurotrophic factor protects retinal ganglion cells from axotomy-induced apoptosis via modulation of retinal glia in vivo

27 June 2018

1 reference

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Macrophage-derived factors stimulate optic nerve regeneration.

27 June 2018

1 reference

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Interleukin-6 (IL-6)--a molecule with both beneficial and destructive potentials

27 June 2018

1 reference

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Purification and characterization of soluble human IL-6 receptor expressed in CHO cells

27 June 2018

1 reference

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Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction

5 September 2018

1 reference

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Interleukin-6 is an efficacious marker of axonal transport disruption during experimental glaucoma and stimulates neuritogenesis in cultured retinal ganglion cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Oncomodulin affords limited regeneration to injured sensory axons in vitro and in vivo.

5 September 2018

1 reference

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What are the principal mediators of optic nerve regeneration after inflammatory stimulation in the eye?

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

SOCS3 deletion promotes optic nerve regeneration in vivo.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Stimulation of axon regeneration in the mature optic nerve by intravitreal application of the toll-like receptor 2 agonist Pam3Cys.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

ROCK inhibition promotes adult retinal ganglion cell neurite outgrowth only in the presence of growth promoting factors.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Cytokine-induced SOCS expression is inhibited by cAMP analogue: impact on regeneration in injured retina

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Exogenous CNTF stimulates axon regeneration of retinal ganglion cells partially via endogenous CNTF.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Interleukin-6 promotes sprouting and functional recovery in lesioned organotypic hippocampal slice cultures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Pressure-induced regulation of IL-6 in retinal glial cells: involvement of the ubiquitin/proteasome pathway and NFkappaB.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Lens injury stimulates adult mouse retinal ganglion cell axon regeneration via both macrophage- and lens-derived factors

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Analysis of the leukemia inhibitory factor receptor functional domains by chimeric receptors and cytokines

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Expression of specific tubulin isotypes increases during regeneration of injured CNS neurons, but not after the application of brain-derived neurotrophic factor (BDNF).

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641349

Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2013.126

Interleukin-6 protects retinal ganglion cells from pressure-induced death

21 January 2018

1 reference

12 December 2020

Role of mTOR in neuroprotection and axon regeneration after inflammatory stimulation

1 reference

12 December 2020

Lens injury stimulates axon regeneration in the mature rat optic nerve

1 reference

12 December 2020

TACE-induced cleavage of NgR and p75NTRin dorsal root ganglion cultures disinhibits outgrowth and promotes branching of neurites in the presence of inhibitory CNS myelin

1 reference

12 December 2020

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

1 reference

12 December 2020

Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis

1 reference

12 December 2020

IL-6 promotes regeneration and functional recovery after cortical spinal tract injury by reactivating intrinsic growth program of neurons and enhancing synapse formation

1 reference

12 December 2020

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

12 December 2020

Taxol facilitates axon regeneration in the mature CNS

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDDIS.2013.126

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

23618907

1 reference