Autoimmunological features in inflammatory cardiomyopathy (Q36822045)

16 August 2017

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title

Autoimmunological features in inflammatory cardiomyopathy (English)

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16 August 2017

Michel Noutsias

4

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Heinz-Peter Schultheiss

6

object named as

Heinz-Peter Schultheiss

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16 August 2017

Angela Kallwellis-Opara

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16 August 2017

Andrea Dörner

2

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16 August 2017

Wolfgang-Christian Poller

3

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16 August 2017

Uwe Kühl

5

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16 August 2017

Mathias Pauschinger

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16 August 2017

22 May 2007

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Clinical Research in Cardiology

16 August 2017

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16 August 2017

96

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16 August 2017

469-480

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16 August 2017

7

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https://scigraph.springernature.com/pub.10.1007/s00392-007-0524-x

16 August 2017

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Lethal autoimmune myocarditis in interferon-gamma receptor-deficient mice: enhanced disease severity by impaired inducible nitric oxide synthase induction.

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Interferon-gamma protects against chronic viral myocarditis by reducing mast cell degranulation, fibrosis, and the profibrotic cytokines transforming growth factor-beta 1, interleukin-1 beta, and interleukin-4 in the heart

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Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure.

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Circulating heart autoantibodies in familial as compared with nonfamilial idiopathic dilated cardiomyopathy.

21 January 2018

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Recombinant murine interleukin-12 facilitates induction of cardiac myosin-specific type 1 helper T cells in rats.

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Susceptibility to myocarditis is dependent on the response of alphabeta T lymphocytes to coxsackieviral infection

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Detection of adenoviral genome in the myocardium of adult patients with idiopathic left ventricular dysfunction

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Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis

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Transfer of human myocarditis into severe combined immunodeficiency mice

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Subclassification of dilated cardiomyopathy and interferon treatment.

21 January 2018

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Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha

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Complement and dilated cardiomyopathy: a role of sublytic terminal complement complex-induced tumor necrosis factor-alpha synthesis in cardiac myocytes

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Identification of alpha- and beta-cardiac myosin heavy chain isoforms as major autoantigens in dilated cardiomyopathy

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Tumor Necrosis Factor Soluble Receptors in Patients With Various Degrees of Congestive Heart Failure

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Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy

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12 December 2020

Cytokine production and antibodies against heat shock protein 60 in cardiomyopathies of different origins

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Disturbance of myocardial energy metabolism in experimental virus myocarditis by antibodies against the adenine nucleotide translocator

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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12 December 2020

Pancreatic expression of interferon-gamma protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis

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12 December 2020

Frequency and quantity of the parvovirus B19 genome in endomyocardial biopsies from patients with suspected myocarditis or idiopathic left ventricular dysfunction

1 reference

12 December 2020

Coxsackievirus induced myocarditis in mice: cardiac myosin autoantibodies do not cross-react with the virus.

1 reference

12 December 2020

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

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12 December 2020

Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation

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12 December 2020

Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin

1 reference

12 December 2020

Heart-specific autoantibodies induced by Coxsackievirus B3: identification of heart autoantigens

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12 December 2020

Potential role of humoral immunity in cardiac dysfunction of patients suffering from dilated cardiomyopathy

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12 December 2020

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12 December 2020

Autoantibodies against cardiac G-protein-coupled receptors define different populations with cardiomyopathies but not with hypertension

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12 December 2020

Role of IL-4 in persistent IgE formation

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12 December 2020

Molecular mimicry: a critical look at exemplary instances in human diseases

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12 December 2020

Circulating cardiac autoantibodies in dilated cardiomyopathy and myocarditis: pathogenetic and clinical significance.

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12 December 2020

The antigenic characteristics and the significance of the adenine nucleotide translocator as a major autoantigen to antimitochondrial antibodies in dilated cardiomyopathy

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12 December 2020

Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy.

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12 December 2020

IL-12 in autoimmunity.

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12 December 2020

Mechanisms of autoimmunity

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12 December 2020

Immunohistological changes in dilated cardiomyopathy induced by immunoadsorption therapy and subsequent immunoglobulin substitution

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12 December 2020

Induction of autoimmunity through bystander effects. Lessons from immunological disorders induced by heavy metals

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12 December 2020

[Dilated cardiomyopathy--a chronic myocarditis? New aspects on diagnosis and therapy]

1 reference

12 December 2020

The Ca-channel as cardiac autoantigen

1 reference

12 December 2020

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

1 reference

12 December 2020

Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway.

1 reference

12 December 2020

Alloimmune IgG binds and modulates cardiac beta-adrenoceptor activity

1 reference

12 December 2020

Protective role for interferon-beta in coxsackievirus B3 infection

1 reference

12 December 2020

Improvement of cardiac function after immunoadsorption in patients with dilated cardiomyopathy

1 reference

12 December 2020

[Autoantibodies against cardiac myosin in patients with myocarditis and dilated cardiomyopathy]

1 reference

12 December 2020

Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease.

1 reference

12 December 2020

Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure

1 reference

12 December 2020

In vivo significance of T cells in the development of Coxsackievirus B3 myocarditis in mice. Immature but antigen-specific T cells aggravate cardiac injury

1 reference

12 December 2020

Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorption

1 reference

12 December 2020

Peptides derived from cardiovascular G-protein-coupled receptors induce morphological cardiomyopathic changes in immunized rabbits.

1 reference

12 December 2020

Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity

1 reference

12 December 2020

Interleukin-10 and the interleukin-10 receptor

1 reference

12 December 2020

High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction.

1 reference

12 December 2020

Temporal expression of pro-inflammatory cytokines and inducible nitric oxide synthase in experimental acute Chagasic cardiomyopathy

1 reference

12 December 2020

Presence of two distinct regions in the coiled-coil structure of the streptococcal Pep M5 protein: relationship to mammalian coiled-coil proteins and implications to its biological properties

1 reference

12 December 2020

Effects of the serum gamma globulin fraction of patients with allergic asthma and dilated cardiomyopathy on chronotropic beta adrenoceptor function in cultured neonatal rat heart myocytes

1 reference

12 December 2020

Molecular mimicry and autoimmunity.

1 reference

12 December 2020

Frequency and specificity of antiheart antibodies in patients with dilated cardiomyopathy detected using SDS-PAGE and western blotting

1 reference

12 December 2020

Visualization of enteroviral replication in myocardial tissue by ultrastructural in situ hybridization: identification of target cells and cytopathic effects

1 reference

12 December 2020

Autoantibodies against vimentin in a murine model of myocarditis.

1 reference

12 December 2020

Pathophysiology of cardiac inflammation: molecular mechanisms

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12 December 2020

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

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12 December 2020

Dilated cardiomyopathy defines serum autoantibodies against G-protein-coupled cardiovascular receptors

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12 December 2020

New therapeutic options in congestive heart failure: Part II.

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12 December 2020

Antibodies against heart muscle and nuclear constituents in cardiomyopathy

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12 December 2020

Cellular and molecular mechanisms in heart failure

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12 December 2020

Plasma cytokine parameters and mortality in patients with chronic heart failure

1 reference

12 December 2020

Induction of multiple heart autoantibodies in mice with coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis

1 reference

12 December 2020

Clinical significance and pathogenic role of anti-cardiac myosin autoantibody in dilated cardiomyopathy

1 reference

12 December 2020

Converging and diverging properties of human interleukin-4 and interleukin-10.

1 reference

12 December 2020

Cardiac autoantibodies to myosin and other heart-specific autoantigens in myocarditis and dilated cardiomyopathy

1 reference

12 December 2020

Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

1 reference

12 December 2020

Immunoglobulin G3 cardiac myosin autoantibodies correlate with left ventricular dysfunction in patients with dilated cardiomyopathy: Immunoglobulin G3 and clinical correlates

1 reference

12 December 2020

Induction of bystander T cell proliferation by viruses and type I interferon in vivo

1 reference

12 December 2020

Antibody-mediated imbalance of myocardial energy metabolism. A causal factor of cardiac failure?

1 reference

12 December 2020

Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

T cell-mediated maintenance of natural self-tolerance: its breakdown as a possible cause of various autoimmune diseases

1 reference

12 December 2020

Reduced oxidative stress in parallel to improved cardiac performance one year after selective removal of anti-beta 1-adrenoreceptor autoantibodies in patients with idiopathic dilated cardiomyopathy: data of a preliminary study

1 reference

12 December 2020

Viral persistence in the myocardium is associated with progressive cardiac dysfunction.

1 reference

12 December 2020

Bystander virus infection prolongs activated T cell survival

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12 December 2020

Myosin-induced acute myocarditis is a T cell-mediated disease

1 reference

12 December 2020

Desmin antibodies in acute infectious myopericarditis

1 reference

12 December 2020

Streptococcal M Protein

1 reference

12 December 2020

Impaired up-regulation of CD25 on CD4+ T cells in IFN-gamma knockout mice is associated with progression of myocarditis to heart failure

1 reference

12 December 2020

Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction

1 reference

12 December 2020

Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failu

1 reference

12 December 2020

Noncytolytic control of viral infections by the innate and adaptive immune response

1 reference

12 December 2020

Immunoregulatory T cells in autoimmunity

1 reference

12 December 2020

Initial and innate responses to viral infections--pattern setting in immunity or disease

1 reference

12 December 2020

Clinical significance of antibodies against tropomyosin, actin and myosin in patients with dilated cardiomyopathy

1 reference

12 December 2020

Parvovirus B19 infection mimicking acute myocardial infarction.

1 reference

12 December 2020

Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

1 reference

12 December 2020

Antimyosin autoantibodies are associated with deterioration of systolic and diastolic left ventricular function in patients with chronic myocarditis

1 reference

12 December 2020

Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy

1 reference

12 December 2020

Immunohistological evidence for a chronic intramyocardial inflammatory process in dilated cardiomyopathy.

1 reference

12 December 2020

Manipulating the Immune System with Immune Globulin

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12 December 2020

[Circulating adhesion molecules (cICAM-1, lcVCAM-1) in patients with suspected inflammatory heart muscle disease]

1 reference

12 December 2020

Immune tolerance to cardiac myosin induced by anti-CD4 monoclonal antibody in autoimmune myocarditis rats

1 reference

12 December 2020

Modulation of beta1-adrenoceptor activity by domain-specific antibodies and heart failure-associated autoantibodies

1 reference

12 December 2020

Dendritic cells: potential triggers of autoimmunity and targets for therapy

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12 December 2020

Characterization of anti-heart antibodies in mice after infection with coxsackie B3 virus

1 reference

12 December 2020

Gene expression profiling during the transition to failure in TNF-alpha over-expressing mice demonstrates the development of autoimmune myocarditis.

1 reference

12 December 2020

Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha

1 reference

12 December 2020

A circulating IgG in Chagas' disease which binds to beta-adrenoceptors of myocardium and modulates their activity

1 reference

12 December 2020

Laminin distribution and autoantibodies to laminin in dilated cardiomyopathy and myocarditis

1 reference

12 December 2020

Relationship of myocardial remodeling to the genesis of serum autoantibodies to cardiac beta(1)-adrenoceptors and muscarinic type 2 acetylcholine receptors in rats

1 reference

12 December 2020

A primer on cytokines: sources, receptors, effects, and inducers

1 reference

12 December 2020

Evidence for autoimmunity to myosin and other heart-specific autoantigens in patients with dilated cardiomyopathy and their relatives

1 reference

12 December 2020

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

1 reference

12 December 2020

New insights into the pathogenesis of dilated cardiomyopathy: possible underlying autoimmune mechanisms and therapy

1 reference

12 December 2020

Autoantibodies in sera of patients with myocarditis: characterization of the corresponding proteins by isoelectric focusing and N-terminal sequence analysis

1 reference

12 December 2020

Autoantibodies against the beta 1-adrenergic receptor in myocarditis and dilated cardiomyopathy: localization of two epitopes

1 reference

12 December 2020

T cell mimicry in inflammatory heart disease

1 reference

12 December 2020

Inflammation, ECG changes and pericardial effusion: whom to biopsy in suspected myocarditis?

1 reference

12 December 2020

Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy

1 reference

12 December 2020

Abnormal expression of histocompatibility and mitochondrial antigens by cardiac tissue from patients with myocarditis and dilated cardiomyopathy

1 reference

12 December 2020

Agonistic effects of anti-peptide antibodies and autoantibodies directed against adrenergic and cholinergic receptors: absence of desensitization

1 reference

12 December 2020

Assessment of immune modulation of β-adrenergic pathways in human dilated cardiomyopathy: Influence of methodologic factors

1 reference

12 December 2020

Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice

1 reference

12 December 2020

Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation

1 reference

12 December 2020

Dual role of the IL-12/IFN-gamma axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-gamma

1 reference

12 December 2020

Antibody-mediated enhancement of calcium permeability in cardiac myocytes

1 reference

12 December 2020

Protection against autoimmune myocarditis by gene transfer of interleukin-10 by electroporation

1 reference

12 December 2020

Antibodies against ADP-ATP carrier enhance Ca2+ current in isolated cardiac myocytes

1 reference

12 December 2020

Hemodynamic improvement and removal of autoantibodies against beta1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy

1 reference

12 December 2020

Identification of mitochondrial antigens recognized by antibodies in sera of patients with idiopathic dilated cardiomyopathy by two-dimensional gel electrophoresis and protein sequencing

1 reference

12 December 2020

Mouse cytomegalovirus infection induces antibodies which cross-react with virus and cardiac myosin: a model for the study of molecular mimicry in the pathogenesis of viral myocarditis

1 reference

12 December 2020

Cytokines that regulate autoimmune myocarditis.

1 reference

12 December 2020

Type I IFN-beta gene therapy suppresses cardiac CD8+ T-cell infiltration during autoimmune myocarditis

1 reference

12 December 2020

Inappropriate major histocompatibility complex expression on cardiac tissue in dilated cardiomyopathy. Relevance for autoimmunity?

1 reference

12 December 2020

Hemodynamic effects of immunoadsorption and subsequent immunoglobulin substitution in dilated cardiomyopathy: three-month results from a randomized study

1 reference

12 December 2020

beta(1)-Adrenoceptor antibodies induce positive inotropic response in isolated cardiomyocytes

1 reference

12 December 2020

Type I interferons keep activated T cells alive

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12 December 2020

Evidence for mimicry by viral antigens in animal models of autoimmune disease including myocarditis

1 reference

12 December 2020

Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure

1 reference

12 December 2020

Potential mechanisms of interferon-alpha induced autoimmunity

1 reference

12 December 2020

Autoantibodies against sarcolemmal Na-K-ATPase in patients with dilated cardiomyopathy: autoimmune basis for ventricular arrhythmias in patients with congestive heart failure

1 reference

12 December 2020

Cytokines and cardiomyocyte death

1 reference

12 December 2020

IL-12 protects against coxsackievirus B3-induced myocarditis by increasing IFN-gamma and macrophage and neutrophil populations in the heart

1 reference

12 December 2020

Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy

1 reference

12 December 2020

The role of type I interferons in the differentiation and function of Th1 and Th2 cells.

1 reference

12 December 2020

Beta1-adrenoceptor antibodies induce apoptosis in adult isolated cardiomyocytes

1 reference

12 December 2020

Short-term hemodynamic effects of immunoadsorption in dilated cardiomyopathy

1 reference

12 December 2020

Tumor necrosis factor in the heart.

1 reference

12 December 2020

Toll-like receptors and their signaling mechanism in innate immunity

1 reference

12 December 2020

Macrophages and the regulation of self-reactive T cells

1 reference

12 December 2020

An overview of tumor necrosis factor alpha and the failing human heart.

1 reference

12 December 2020

Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors.

1 reference

12 December 2020

Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo

1 reference

12 December 2020

Epitope mapping of the branched chain alpha-ketoacid dehydrogenase dihydrolipoyl transacylase (BCKD-E2) protein that reacts with sera from patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions

1 reference

12 December 2020

[Detection of enteroviral RNA in endomyocardial biopsies in inflammatory cardiomyopathy and idiopathic dilated cardiomyopathy].

1 reference

12 December 2020

Microbial products induce autoimmune disease by an IL-12-dependent pathway

1 reference

12 December 2020

Identification of a putative shared epitope between Coxsackie virus B4 and alpha cardiac myosin heavy chain

1 reference

12 December 2020

Anti-beta-receptor antibodies in human dilated cardiomyopathy and correlation with HLA-DR antigens

1 reference

12 December 2020

10.1007/S00392-007-0524-X

Identifiers

DOI

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16 August 2017

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