Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology (Q36827835)

16 August 2017

1 reference

title

Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology (English)

1 reference

16 August 2017

1 reference

Jonathan R Seckl

1

1 reference

PubMed ID

17515892

16 August 2017

Megan C Holmes

series ordinal

2

1 reference

16 August 2017

1 June 2007

1 reference

Nature Clinical Practice Endocrinology and Metabolism

16 August 2017

1 reference

16 August 2017

3

1 reference

16 August 2017

479-488

1 reference

16 August 2017

6

1 reference

The developmental origins of adult disease

16 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

The Metabolic Clearance Rate, Blood Production, Interconversion and Transplacental Passage of Cortisol and Cortisone in Pregnancy Near Term

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

Low birth weight predicts elevated plasma cortisol concentrations in adults from 3 populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

The programming of individual differences in defensive responses and reproductive strategies in the rat through variations in maternal care

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Living with the past: evolution, development, and patterns of disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Transgenerational induction of defences in animals and plants

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Concentrations of corticotrophin-releasing hormone in the umbilical-cord blood of pregnancies complicated by pre-eclampsia

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Childhood growth and age at menarche.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Evolution, development and timing of puberty

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Fetal nutrition and cardiovascular disease in adult life

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Sex Steroid Induced Changes in Hepatic Enzymes

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Prenatal glucocorticoids and long-term programming

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoid exposure in utero: new model for adult hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Maternal glucocorticoid treatment programs HPA regulation in adult offspring: sex-specific effects

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Maternal asthma as a model for examining fetal sex-specific effects on maternal physiology and placental mechanisms that regulate human fetal growth.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Prenatal dexamethasone causes oligonephronia, sodium retention, and higher blood pressure in the offspring

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Placental 11 beta-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Inhibition of 11β-Hydroxysteroid Dehydrogenase in Pregnant Rats and the Programming of Blood Pressure in the Offspring

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Inhibition of 11beta-hydroxysteroid dehydrogenase, the foeto-placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety-like behaviour in the offspring

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

The mother or the fetus? 11beta-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Gene structure and chromosomal localization of the human HSD11K gene encoding the kidney (type 2) isozyme of 11 beta-hydroxysteroid dehydrogenase

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Oxygen regulation of placental 11 beta-hydroxysteroid dehydrogenase 2: physiological and pathological implications

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

The effects of chorioamnionitis and betamethasone on 11beta hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor in preterm human placenta

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoids stimulate the expression of 11beta-hydroxysteroid dehydrogenase type 2 in cultured human placental trophoblast cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Cadmium reduces 11 beta-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Organotins disrupt the 11beta-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Alterations in placental 11 beta-hydroxysteroid dehydrogenase (11 betaHSD) activities and fetal cortisol:cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Neonatal leptin treatment reverses developmental programming

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoid regulation of human and ovine parturition: the relationship between fetal hypothalamic-pituitary-adrenal axis activation and intrauterine prostaglandin production

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Cortisol blockade of progesterone: a possible molecular mechanism involved in the initiation of human labor

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Enhancement of glucocorticoid-induced 11beta-hydroxysteroid dehydrogenase type 1 expression by proinflammatory cytokines in cultured human amnion fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Type 2 11 beta-hydroxysteroid dehydrogenase in foetal and adult life

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Epigenetic programming by maternal behavior

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

The intergenerational effects of fetal programming: non-genomic mechanisms for the inheritance of low birth weight and cardiovascular risk

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'?

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Glucocorticoid-induced DNA demethylation and gene memory during development

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Cardiovascular risk factors after antenatal exposure to betamethasone: 30-year follow-up of a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Effects of early prenatal dexamethasone on the cognitive and behavioral development of young children: results of a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Repeated antenatal corticosteroids: size at birth and subsequent development.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Size at birth and adrenocortical function in childhood.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Structure of the glucocorticoid receptor (NR3C1) gene 5' untranslated region: identification, and tissue distribution of multiple new human exon 1

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Post-traumatic stress disorder

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Enhanced sensitivity to glucocorticoids in peripheral mononuclear leukocytes in posttraumatic stress disorder

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the World Trade Center attacks during pregnancy

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

The World Trade Center disaster and intrauterine growth restriction

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Psychological trauma associated with the World Trade Center attacks and its effect on pregnancy outcome

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0515

7 January 2021

Identifiers

DOI

10.1038/NCPENDMET0515

1 reference

16 August 2017

1 reference

PubMed ID

17515892