HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2 (Q36834531)

16 August 2017

HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2 (English)

1 reference

16 August 2017

hepatocellular carcinoma

1 reference

Yanmei Chen

1

1 reference

16 August 2017

Chengzhao Lin

series ordinal

2

1 reference

16 August 2017

Yang Liu

series ordinal

3

1 reference

16 August 2017

Yan Jiang

series ordinal

4

1 reference

16 August 2017

24 October 2015

1 reference

16 August 2017

1 reference

16 August 2017

37

1 reference

16 August 2017

4

1 reference

16 August 2017

4399-4408

1 reference

Creative Commons Attribution 4.0 International

16 August 2017

start time

24 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4844642/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway

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29 September 2017

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The association of HMGB1 gene with the prognosis of HCC.

29 September 2017

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HMGB1 plays a critical role in vascular inflammation and lesion formation via toll-like receptor 9.

29 September 2017

1 reference

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HMGB1: A Promising Therapeutic Target for Prostate Cancer

29 September 2017

1 reference

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29 September 2017

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High mobility group B1 protein interacts with its receptor RAGE in tumor cells but not in normal tissues

29 September 2017

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Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A).

29 September 2017

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High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases

29 September 2017

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Reduced high-mobility group box 1 expression induced by RNA interference inhibits the bioactivity of hepatocellular carcinoma cell line HCCLM3.

29 September 2017

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The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis-Binding Myc makes the difference

29 September 2017

1 reference

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Effect of HMGB1 silencing on cell proliferation, invasion and apoptosis of MGC-803 gastric cancer cells

29 September 2017

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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

29 September 2017

1 reference

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29 September 2017

Global cancer statistics

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Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer

29 September 2017

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High-mobility group box 1 and cancer

29 September 2017

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High-mobility group box 1-mediated matrix metalloproteinase-9 expression in non-small cell lung cancer contributes to tumor cell invasiveness

29 September 2017

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Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells.

29 September 2017

1 reference

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RAGE as a receptor of HMGB1 (Amphoterin): roles in health and disease

29 September 2017

1 reference

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Lost in transcription: p21 repression, mechanisms, and consequences

29 September 2017

1 reference

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C-Myc-independent restoration of multiple phenotypes by two C-Myc target genes with overlapping functions

29 September 2017

1 reference

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Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway

29 September 2017

1 reference

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Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function

29 September 2017

1 reference

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Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal

29 September 2017

1 reference

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis

29 September 2017

1 reference

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An alternative pathway for gene regulation by Myc

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

p53/HMGB1 complexes regulate autophagy and apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

Effect of Bcl-2 and Bax on survival of side population cells from hepatocellular carcinoma cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

Thrombomodulin's lectin-like domain reduces myocardial damage by interfering with HMGB1-mediated TLR2 signalling.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

High mobility group box 1 protein is methylated and transported to cytoplasm in clear cell renal cell carcinoma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

Invasion potential of H22 hepatocarcinoma cells is increased by HMGB1-induced tumor NF-κB signaling via initiation of HSP70.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

HMGB1: The Central Cytokine for All Lymphoid Cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

The expression of HMGB1 protein and its receptor RAGE in human malignant tumors

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

Increased expression of high mobility group box 1 (HMGB1) is associated with progression and poor prognosis in human nasopharyngeal carcinoma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

The binding interaction of HMG-1 with the TATA-binding protein/TATA complex.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844642

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS13277-015-4049-Z

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS13277-015-4049-Z

Serum high mobility group box chromosomal protein 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma

21 January 2018

1 reference

12 December 2020

Variation of HMGB1 expression in breast cancer

1 reference

12 December 2020

Cytosolic HMGB1 expression in human renal clear cell cancer indicates higher pathological T classifications and tumor grades

1 reference

12 December 2020

Activation of gene expression in human neutrophils by high mobility group box 1 protein

1 reference

12 December 2020

10.1007/S13277-015-4049-Z

Identifiers

DOI

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

26499944

1 reference