The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia (Q36849336)

16 August 2017

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title

The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia (English)

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16 August 2017

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Kay NE

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16 August 2017

O'Brien SM

series ordinal

2

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16 August 2017

Pettitt AR

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3

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16 August 2017

Stilgenbauer S

series ordinal

4

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16 August 2017

14 June 2007

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16 August 2017

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16 August 2017

21

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9

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16 August 2017

1885-1891

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2404802

16 August 2017

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21 January 2018

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CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

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Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy

21 January 2018

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Allogeneic Stem-Cell Transplantation May Overcome the Adverse Prognosis of UnmutatedVHGene in Patients With Chronic Lymphocytic Leukemia

21 January 2018

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21 January 2018

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CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation.

21 January 2018

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ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype

21 January 2018

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Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

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ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

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Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL.

21 January 2018

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High frequency of p53 dysfunction and low level of VH mutation in chronic lymphocytic leukemia patients using the VH3-21 gene segment

21 January 2018

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Imperfect correlation between p53 dysfunction and deletion of TP53 and ATM in chronic lymphocytic leukaemia.

21 January 2018

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Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia.

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Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia.

21 January 2018

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Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia.

21 January 2018

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Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions

21 January 2018

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Update on risk-stratified management for chronic lymphocytic leukemia

21 January 2018

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Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

Serum beta(2)-microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukemia and immunocytoma

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7 January 2021

Unmutated immunoglobulin variable heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia

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7 January 2021

Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia

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7 January 2021

CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia

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7 January 2021

CD49d in B-cell chronic lymphocytic leukemia: correlated expression with CD38 and prognostic relevance

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7 January 2021

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

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7 January 2021

Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia

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7 January 2021

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7 January 2021

Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status

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7 January 2021

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7 January 2021

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7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

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7 January 2021

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

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7 January 2021

Cytogenetic abnormalities can change during the course of the disease process in chronic lymphocytic leukemia

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7 January 2021

Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromosomal aberrations in 80% of CLL patients: A study of 132 CLL cases with correlation to FISH, IgVH status, and CD38 expression

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7 January 2021

Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404802

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release_n3wiebz67zcxllghng26qgm2dq

16 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/n3wiebz67zcxllghng26qgm2dq

24 November 2022

mapped directly with Wikidata item

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