Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene (Q36851389)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2907606%20AND%20SRC:MED&resulttype=core&format=json

7 October 2019

title

Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene (English)

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7 October 2019

1

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7 October 2019

author name string

C R King

2

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7 October 2019

J H Pierce

3

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7 October 2019

P P Di Fiore

4

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7 October 2019

S A Aaronson

5

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7 October 2019

language of work or name

English

0 references

publication date

1 December 1988

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2907606%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

7 October 2019

published in

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7 October 2019

volume

8

1 reference

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7 October 2019

page(s)

5570-5574

1 reference

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7 October 2019

issue

12

1 reference

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Rapid and efficient site-specific mutagenesis without phenotypic selection

7 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

29 September 2017

1 reference

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Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Identification and biochemical characterization of p70TRK, product of the human TRK oncogene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

29 September 2017

1 reference

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The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

The neu oncogene encodes an epidermal growth factor receptor-related protein

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

The transmembrane segment of the human transferrin receptor functions as a signal peptide.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Amplification of a novel v-erbB-related gene in a human mammary carcinoma.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

A membrane-anchored cytoplasmic domain of the human insulin receptor mediates a constitutively elevated insulin-independent uptake of 2-deoxyglucose.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365664

The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2907606

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2907606

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.8.12.5570

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2907606%20AND%20SRC:MED&resulttype=core&format=json

7 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2907606%20AND%20SRC:MED&resulttype=core&format=json

7 October 2019

1 reference