Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring. (Q36852850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978279%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

title

Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring (English)

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24 November 2019

3

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24 November 2019

author name string

Wei Yang

1

1 reference

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24 November 2019

Motomu Shimaoka

2

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24 November 2019

Junichi Takagi

4

1 reference

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24 November 2019

Timothy A Springer

5

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24 November 2019

language of work or name

English

0 references

publication date

20 February 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978279%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

24 November 2019

published in

1 reference

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24 November 2019

volume

101

1 reference

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24 November 2019

issue

9

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24 November 2019

page(s)

2906-2911

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Structure of integrin alpha5beta1 in complex with fibronectin

24 November 2019

cites work

1 reference

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29 September 2017

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Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds.

29 September 2017

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Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere

29 September 2017

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Conformational regulation of integrin structure and function

29 September 2017

1 reference

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Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

29 September 2017

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

29 September 2017

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Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition

29 September 2017

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

29 September 2017

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Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

29 September 2017

1 reference

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Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation

29 September 2017

1 reference

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Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

29 September 2017

1 reference

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An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

29 September 2017

1 reference

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29 September 2017

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Computational design of an integrin I domain stabilized in the open high affinity conformation

29 September 2017

1 reference

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NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

29 September 2017

1 reference

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Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain

29 September 2017

1 reference

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Structural basis of collagen recognition by integrin alpha2beta1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365718

Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain

29 September 2017

1 reference

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Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.

29 September 2017

1 reference

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Leukocyte adhesion--structure and function of human leukocyte beta2-integrins and their cellular ligands

29 September 2017

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Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

29 September 2017

1 reference

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A discrete site modulates activation of I domains. Application to integrin alphaMbeta2.

29 September 2017

1 reference

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Two conformations of the integrin A-domain (I-domain): a pathway for activation?

29 September 2017

1 reference

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Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

29 September 2017

1 reference

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Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits

29 September 2017

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Antibody against the Leu-CAM beta-chain (CD18) promotes both LFA-1- and CR3-dependent adhesion events

29 September 2017

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Using studies on tryptophan metabolism to answer basic biological questions

27 June 2018

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Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

21 January 2018

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Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other

21 January 2018

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The role of the CPNKEKEC sequence in the beta(2) subunit I domain in regulation of integrin alpha(L)beta(2) (LFA-1).

21 January 2018

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

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Cellular activation of leukocyte function-associated antigen-1 and its affinity are regulated at the I domain allosteric site

21 January 2018

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Does the integrin alphaA domain act as a ligand for its betaA domain?

21 January 2018

1 reference

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The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14978279

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0307340101

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j3la6a7mrffwlo64irhqxi6klu

30 July 2022

release_j3la6a7mrffwlo64irhqxi6klu

ADS bibcode

2004PNAS..101.2906Y

0 references

Fatcat ID

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Fatcat

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30 July 2022

https://api.fatcat.wiki/v0/release/j3la6a7mrffwlo64irhqxi6klu

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/j3la6a7mrffwlo64irhqxi6klu

1 reference

30 July 2022