Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease (Q36855099)

16 August 2017

Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease (English)

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16 August 2017

10

Erwin W Gelfand

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16 August 2017

Yi Jia

1

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16 August 2017

Joanne Domenico

2

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16 August 2017

Katsuyuki Takeda

3

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16 August 2017

Junyan Han

4

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16 August 2017

Meiqin Wang

5

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16 August 2017

Michael Armstrong

6

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16 August 2017

Nichole Reisdorph

7

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16 August 2017

Brian P O'Connor

8

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16 August 2017

Joseph J Lucas

9

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16 August 2017

language of work or name

English

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publication date

29 April 2013

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

110

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16 August 2017

20

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16 August 2017

8152-8157

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3657775/fullTextXML

inferred from PubMed Central ID database lookup

cites work

IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction

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Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation

29 September 2017

1 reference

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Innate and adaptive immune responses in asthma

29 September 2017

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Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity

29 September 2017

1 reference

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Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3

29 September 2017

1 reference

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Synergistic and combinatorial control of T cell activation and differentiation by transcription factors

29 September 2017

1 reference

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Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B

29 September 2017

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How are T(H)1 and T(H)2 effector cells made?

29 September 2017

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Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc

29 September 2017

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Mutation of mouse Cyp11a1 promoter caused tissue-specific reduction of gene expression and blunted stress response without affecting reproduction

29 September 2017

1 reference

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ATF2 impairs glucocorticoid receptor-mediated transactivation in human CD8+ T cells.

29 September 2017

1 reference

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The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial

29 September 2017

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Homozygous mutation of P450 side-chain cleavage enzyme gene (CYP11A1) in 46, XY patient with adrenal insufficiency, complete sex reversal, and agenesis of corpus callosum

29 September 2017

1 reference

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CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma

29 September 2017

1 reference

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Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology?

29 September 2017

1 reference

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Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization

29 September 2017

1 reference

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17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism

29 September 2017

1 reference

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Biosynthesis and assay of neurosteroids in rats and mice: functional correlates.

29 September 2017

1 reference

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Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles

29 September 2017

1 reference

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

29 September 2017

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An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.

29 September 2017

1 reference

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CD8+ T cells can be primed in vitro to produce IL-4

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Antigen-specific effector CD8 T cells regulate allergic responses via IFN-γ and dendritic cell function.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Corticosteroids enhance CD8+ T cell-mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1.

4 September 2018

1 reference

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Cutting edge: the development of IL-4-producing B cells (B effector 2 cells) is controlled by IL-4, IL-4 receptor alpha, and Th2 cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Bronchial CD8 cell infiltrate and lung function decline in asthma.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Contribution of antigen-primed CD8+ T cells to the development of airway hyperresponsiveness and inflammation is associated with IL-13.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities

4 September 2018

1 reference

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Virus-specific CD8+ cells can switch to interleukin 5 production and induce airway eosinophilia

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657775

Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways

4 September 2018

1 reference

12 December 2020

Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness

1 reference

12 December 2020

CD8+ T cell-mediated airway hyperresponsiveness and inflammation is dependent on CD4+IL-4+ T cells

1 reference

12 December 2020

Allergen-specific CTL require perforin expression to suppress allergic airway inflammation

1 reference

12 December 2020

Breakdown of Th cell immune responses and steroidogenic CYP11A1 expression in CD4+ T cells in a murine model implanted with B16 melanoma

1 reference

12 December 2020

Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1216671110

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16 August 2017

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16 August 2017

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