Control points in NKT-cell development (Q36858868)

16 August 2017

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title

Control points in NKT-cell development (English)

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16 August 2017

Dale I Godfrey

1

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author name string

Stuart P Berzins

series ordinal

2

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16 August 2017

1 July 2007

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Nature Reviews Immunology

16 August 2017

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16 August 2017

7

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16 August 2017

505-518

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16 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nri2116

16 August 2017

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cites work

NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.

1 reference

NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation

21 January 2018

1 reference

Efficient activation of Valpha14 invariant NKT cells by foreign lipid antigen is associated with concurrent dendritic cell-specific self recognition

21 January 2018

1 reference

Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids

21 January 2018

1 reference

Valpha24-JalphaQ-independent, CD1d-restricted recognition of alpha-galactosylceramide by human CD4(+) and CD8alphabeta(+) T lymphocytes.

21 January 2018

1 reference

The Paradox of Immune Molecular Recognition of α-Galactosylceramide: Low Affinity, Low Specificity for CD1d, High Affinity for αβ TCRs

21 January 2018

1 reference

NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes.

21 January 2018

1 reference

Long-term retention of mature NK1.1+ NKT cells in the thymus.

21 January 2018

1 reference

A cell-type specific CD1d expression program modulates invariant NKT cell development and function

21 January 2018

1 reference

The influence of CD1d in postselection NKT cell maturation and homeostasis

21 January 2018

1 reference

Membrane lymphotoxin is required for the development of different subpopulations of NK T cells.

21 January 2018

1 reference

Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B.

21 January 2018

1 reference

Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.

21 January 2018

1 reference

Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny

21 January 2018

1 reference

Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development

21 January 2018

1 reference

GATA-3 regulates the development and function of invariant NKT cells

21 January 2018

1 reference

Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus.

21 January 2018

1 reference

CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

21 January 2018

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Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

21 January 2018

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NKT cells: what's in a name?

21 January 2018

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Going both ways: immune regulation via CD1d-dependent NKT cells

31 March 2020

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Development of Valpha4+ NK T cells in the early stages of embryogenesis

31 March 2020

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Induction of differentiation of pre-NKT cells to mature Valpha14 NKT cells by granulocyte/macrophage colony-stimulating factor

31 March 2020

1 reference

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

31 March 2020

1 reference

Thymic dependence of invariant Vα14+ Natural Killer-T cell development

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Three day neonatal thymectomy selectively depletes NK1.1+ T cells

1 reference

Characterization of the early stages of thymic NKT cell development

31 March 2020

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NKT cells derive from double-positive thymocytes that are positively selected by CD1d

31 March 2020

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Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors

31 March 2020

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Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny

31 March 2020

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An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

31 March 2020

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Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells

31 March 2020

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Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice

31 March 2020

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Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes

31 March 2020

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Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes

31 March 2020

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T Cell Development in Mice Expressing CD1d Directed by a Classical MHC Class II Promoter

31 March 2020

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Expression of CD1d Under the Control of a MHC Class Ia Promoter Skews the Development of NKT Cells, But Not CD8+ T Cells

31 March 2020

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Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes

31 March 2020

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An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population

31 March 2020

1 reference

31 March 2020

The biology of NKT cells

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Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency

31 March 2020

1 reference

Lysosomal glycosphingolipid recognition by NKT cells

31 March 2020

1 reference

Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligands

31 March 2020

1 reference

Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognition

31 March 2020

1 reference

Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3).

31 March 2020

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Thio-isoglobotrihexosylceramide, an agonist for activating invariant natural killer T cells.

31 March 2020

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Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.

31 March 2020

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Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases

31 March 2020

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Differential alteration of lipid antigen presentation to NKT cells due to imbalances in lipid metabolism

31 March 2020

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Chewing the fat on natural killer T cell development.

31 March 2020

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Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency

31 March 2020

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Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals

31 March 2020

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Positive and negative selection of T cells

31 March 2020

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Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone size

31 March 2020

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An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells

31 March 2020

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Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain

31 March 2020

1 reference

Development of CD1d-restricted NKT cells in the mouse thymus.

31 March 2020

1 reference

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

31 March 2020

1 reference

Cutting edge: influence of the TCR V beta domain on the avidity of CD1d:alpha-galactosylceramide binding by invariant V alpha 14 NKT cells

31 March 2020

1 reference

CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells

31 March 2020

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Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide

31 March 2020

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Negative selection in the thymus includes semimature T cells

31 March 2020

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T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells

31 March 2020

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CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.

31 March 2020

1 reference

A subset of CD4+ thymocytes selected by MHC class I molecules

31 March 2020

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Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining

31 March 2020

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Distinct functional lineages of human V(alpha)24 natural killer T cells

31 March 2020

1 reference

Differential antitumor immunity mediated by NKT cell subsets in vivo

31 March 2020

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Regulatory roles of NKT cells in the induction and maintenance of cyclophosphamide-induced tolerance

31 March 2020

1 reference

Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7

31 March 2020

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Distinct homeostatic requirements of CD4+ and CD4- subsets of Valpha24-invariant natural killer T cells in humans

31 March 2020

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Limited correlation between human thymus and blood NKT?cell content revealed by an ontogeny study of paired tissue samples

31 March 2020

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Comparative gene expression analysis of NKT cell subpopulations

31 March 2020

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Differential proliferative response of NKT cell subpopulations to in vitro stimulation in presence of different cytokines

31 March 2020

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Analysis of the effect of different NKT cell subpopulations on the activation of CD4 and CD8 T cells, NK cells, and B cells

31 March 2020

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Homeostasis of V alpha 14i NKT cells

31 March 2020

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IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

31 March 2020

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IL-15 availability conditions homeostasis of peripheral natural killer T cells

31 March 2020

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The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells

31 March 2020

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T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.

31 March 2020

1 reference

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

31 March 2020

1 reference

A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cells

31 March 2020

1 reference

Requirement for membrane lymphotoxin in natural killer cell development.

31 March 2020

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Increased thymic B cells but maintenance of thymic structure, T cell differentiation and negative selection in lymphotoxin-alpha and TNF gene-targeted mice

31 March 2020

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NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells

31 March 2020

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Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

31 March 2020

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Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

31 March 2020

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The Src family tyrosine kinase Fyn regulates natural killer T cell development

31 March 2020

1 reference

Regulation of NKT cell development by SAP, the protein defective in XLP

31 March 2020

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Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

31 March 2020

1 reference

Signaling for NKT cell development: the SAP-FynT connection

31 March 2020

1 reference

Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

31 March 2020

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The cell surface receptor SLAM controls T cell and macrophage functions

31 March 2020

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Slamf1, the NKT cell control gene Nkt1

31 March 2020

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Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: improved Valpha14-NKT cell performance but failure to protect against type 1 diabetes

31 March 2020

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Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.

31 March 2020

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MTP regulated by an alternate promoter is essential for NKT cell development

31 March 2020

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A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d

31 March 2020

1 reference

The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells

31 March 2020

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Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

31 March 2020

1 reference

Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells

31 March 2020

1 reference

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

31 March 2020

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In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

31 March 2020

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CD1d-Restricted NKT Cells: An Interstrain Comparison

31 March 2020

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

31 March 2020

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Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies

31 March 2020

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Testing the NKT cell hypothesis of human IDDM pathogenesis

31 March 2020

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Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

31 March 2020

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Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells

31 March 2020

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Cutting edge: impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein

31 March 2020

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Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2

31 March 2020

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Thymocyte expression of cathepsin L is essential for NKT cell development

31 March 2020

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Lineage relationships and differentiation of natural killer (NK) T cells: intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 molecules

31 March 2020

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DOCK2 is required in T cell precursors for development of Valpha14 NK T cells

31 March 2020

1 reference

Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in mice

31 March 2020

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The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells

31 March 2020

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XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome

31 March 2020

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Targeted expression of human CD1d in transgenic mice reveals independent roles for thymocytes and thymic APCs in positive and negative selection of Valpha14i NKT cells

31 March 2020

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A thymic precursor to the NK T cell lineage

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI2116

1 reference

PubMed ID

17589542

Dimensions Publication ID

16 August 2017

0 references

1 reference

PubMed ID

17589542