Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex. (Q36862444)

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scientific article published on 12 August 2008

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English	Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex.	scientific article published on 12 August 2008

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12 January 2020

Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex (English)

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12 January 2020

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12 January 2020

Robert A Stockley

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Robert A Stockley

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12 January 2020

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Anita L Sullivan

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12 January 2020

Pieter S Hiemstra

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12 January 2020

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12 August 2008

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12 January 2020

Respiratory Research

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12 January 2020

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12 January 2020

60

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12 January 2020

Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding

1 reference

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29 September 2017

Secretory Leukocyte Protease Inhibitor Binds to Annexin II, a Cofactor for Macrophage HIV-1 Infection

1 reference

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29 September 2017

Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions

1 reference

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29 September 2017

Secretory leucoprotease inhibitor impairs Toll-like receptor 2- and 4-mediated responses in monocytic cells

1 reference

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Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis

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Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)

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Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands

1 reference

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1 reference

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Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections

1 reference

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Identification of a novel secretory leukocyte protease inhibitor-binding protein involved in membrane phospholipid movement

1 reference

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Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers

1 reference

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29 September 2017

The Protein Data Bank

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29 September 2017

The interrelationship of sputum inflammatory markers in patients with chronic bronchitis

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29 September 2017

Secretory leukocyte protease inhibitor interferes with uptake of lipopolysaccharide by macrophages.

1 reference

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29 September 2017

Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis

1 reference

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29 September 2017

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

29 September 2017

Antibacterial activity of antileukoprotease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

29 September 2017

Potential role of recombinant secretory leucoprotease inhibitor in the prevention of neutrophil mediated matrix degradation

1 reference

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29 September 2017

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

29 September 2017

Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

29 September 2017

The 2.5 A X-ray crystal structure of the acid-stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha-chymotrypsin

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29 September 2017

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

1 reference

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Secretory leukocyte protease inhibitor binding to mRNA and DNA as a possible cause of toxicity to Escherichia coli

1 reference

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29 September 2017

Expression of the secretory leukoprotease inhibitor gene in epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

29 September 2017

The elastase-induced expression of secretory leukocyte protease inhibitor is decreased in remodelled airway epithelium

1 reference

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27 June 2018

Neutrophil elastase increases secretory leukocyte protease inhibitor transcript levels in airway epithelial cells

1 reference

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Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes

1 reference

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Human bronchial leucocyte proteinase inhibitor. Rapid isolation and kinetic analysis with human leucocyte proteinases

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Influence of elastin on the inhibition of leucocyte elastase by alpha 1-proteinase inhibitor and bronchial inhibitor. Potent inhibition of elastin-bound elastase by bronchial inhibitor

1 reference

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Proteinase/proteinase inhibitor imbalance in sputum sol phases from patients with chronic obstructive pulmonary disease. Suggestions for a key role played by antileukoprotease

1 reference

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27 June 2018

Interaction between secretory leucocyte proteinase inhibitor and bronchial mucins or glycopeptides. Physiopathological implications for the protection of mucins against proteolysis by human leucocyte elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529288

27 June 2018

Isolation and partial characterization of a low molecular weight acid stable protease inhibitor from human bronchial secretion

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A Rapid Procedure for the Large Scale Purification of Elastase and Cathepsin G from Human Sputum

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4 September 2018

Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination.

1 reference

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4 September 2018

Antileukoprotease in sputum during bronchial infections

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Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

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Cytokines regulate membrane-bound leukocyte elastase on neutrophils: a novel mechanism for effector activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antileukoprotease: an endogenous protein in the innate mucosal defense against fungi

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha(1)-antitrypsin deficiency (PiZ)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antileukoprotease is associated with elastin fibers in the extracellular matrix of the human lung. An immunoelectron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elastase inhibitors of the respiratory tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/18699987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1465-9921-9-60

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18699987%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18699987%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18699987%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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