Growth factor and oncogene signalling pathways as targets for rational anticancer drug development (Q36869379)

16 August 2017

1 reference

title

Growth factor and oncogene signalling pathways as targets for rational anticancer drug development (English)

1 reference

16 August 2017

G. Powis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1760877

17 November 2022

A. Kozikowski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1760877

17 November 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1760877

17 November 2022

publication date

1 October 1991

1 reference

full work available at URL

16 August 2017

https://api.elsevier.com/content/article/PII:S0009912005800141?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

https://api.elsevier.com/content/article/PII:S0009912005800141?httpAccept=text/plain

17 November 2022

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

17 November 2022

published in

Clinical Biochemistry

1 reference

16 August 2017

24

1 reference

16 August 2017

5

1 reference

16 August 2017

385-397

1 reference

Genetic and cellular basis of multistep carcinogenesis

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Polypeptide growth factors: roles in normal and abnormal cell growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Oncogenes and cellular signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Oncogenes, growth factors, and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Signal transduction by receptors with tyrosine kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Binding of GAP to activated PDGF receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Early changes in inositol lipids and their metabolites induced by platelet-derived growth factor in quiescent Swiss mouse 3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Contribution of external and internal Ca2+ to changes in intracellular free Ca2+ produced by mitogens in Swiss 3T3 fibroblasts: the role of dihydropyridine sensitive Ca2+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

The role of protein kinase C in cell surface signal transduction and tumour promotion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Platelet-derived growth factor elicits cyclic AMP accumulation in swiss 3T3 cells: Role of prostaglandin production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Role of stimulation of arachidonic acid release in the proliferative response of 3T3 mouse fibroblasts to platelet-derived growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Eicosanoid synthesis in platelet-derived growth factor-stimulated fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

PDGF-induced activation of phospholipase C is not required for induction of DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Effects of platelet-derived growth factor and fibroblast growth factor on free intracellular calcium and mitogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Inositol phosphates and cell signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Inositol phosphate formation and its relationship to calcium signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Does inositol tetrakisphosphate play a role in the receptor-mediated control of calcium mobilization?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Inositol phosphate and Ca2+ flow

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Phosphatidylinositol kinase activity associates with viral p60src protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Role of phosphatidylinositol kinase in PDGF receptor signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

The antiproliferative effects of staurosporine are not exclusively mediated by inhibition of protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Staurosporine inhibition of intracellular free Ca2+ transients in mitogen-stimulated Swiss 3T3 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Characterization of receptor tyrosine-specific protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Signal transduction by the platelet-derived growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Effects of antineoplastic ether lipids on model and biological membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Platelet-derived growth factor blocks the increase in intracellular free Ca2+ caused by calcium ionophores and a volatile anesthetic agent in Swiss 3T3 fibroblasts without altering toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Irreversible inhibition of v-src tyrosine kinase activity by herbimycin A and its abrogation by sulfhydryl compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Specific inhibitors of tyrosine-specific protein kinase, synthetic 4-hydroxycinnamamide derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Antineoplastic Components of Marine Animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Suramin, an anti-cancer drug, inhibits protein kinase C and induces differentiation in neuroblastoma cell clone NB2A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Suramin blocks intracellular Ca2+ release and growth factor-induced increases in cytoplasmic free Ca2+ concentration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2805%2980014-1

Peptide growth factors: current status and therapeutic opportunities

7 January 2021

9

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Phosphoinositide metabolism and the control of cell proliferation

17 November 2022

10

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Activation of phosphatidylinositol 3-kinase by insulin

17 November 2022

42

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation

17 November 2022

44

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

17 November 2022

46

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Phosphatidylinositol kinase type I activity associates with various oncogene products

17 November 2022

49

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Elevation of leukemic cell intracellular calcium by the ether lipid SRI 62-834

17 November 2022

75

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Phospholipase C isozymes: structural and functional similarities

17 November 2022

82

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Genistein, a specific inhibitor of tyrosine-specific protein kinases

17 November 2022

87

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

Suramin: prototype of a new generation of antitumor compounds

17 November 2022

97

1 reference

https://api.crossref.org/works/10.1016/S0009-9120(05)80014-1

17 November 2022

Identifiers

1 reference

16 August 2017

1 reference