Endothelial dysfunction: does it matter? Is it reversible? (Q36874825)

16 August 2017

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title

Endothelial dysfunction: does it matter? Is it reversible? (English)

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16 August 2017

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Celermajer DS

1

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PubMed ID

9247501

16 August 2017

language of work or name

English

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publication date

1 August 1997

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Journal of the American College of Cardiology

16 August 2017

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16 August 2017

30

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16 August 2017

325-333

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16 August 2017

2

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The role of endothelium in cardiovascular homeostasis and diseases.

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelial cell dysfunction: an emerging endocrinopathy linked to coronary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Is NO an endogenous antiatherogenic molecule?

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Multiple pathways of capillary permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Choices among the possible reaction routes catalyzed by thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

1 reference

7 January 2021

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Cell biology of endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Nucleotide metabolism by endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Fibrinolytic pathways and the endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Vascular endothelial cells synthesize nitric oxide from L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Role of endothelium in the maintenance of low pulmonary vascular tone in normal children

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Crucial role of endothelium in the vasodilator response to increased flow in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The nature of endothelium-derived vascular relaxant factor

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-derived relaxing factor alters calcium fluxes in rabbit aorta: a cyclic guanosine monophosphate-mediated effect

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-dependent hyperpolarization of canine coronary smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-derived hyperpolarizing factor: a new endogenous inhibitor from the vascular endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Estimated rate of prostacyclin secretion into the circulation of normal man

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The fate of radioiodinated endothelin-1 and endothelin-3 in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

A sensitive radioimmunoassay measuring endothelin-like immunoreactivity in human plasma: comparison of levels in patients with essential hypertension and normotensive control subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelin in renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The potential role of endothelin as a vasoconstrictor substance in congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Paracrine coronary endothelial control of left ventricular function in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelial function in human coronary arteries in vivo. Focus on hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Close relation of endothelial function in the human coronary and peripheral circulations

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The pathogenesis of atherosclerosis: a perspective for the 1990s

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

A technique to investigate surface morphology and endothelial cell replication of small arteries: a study in acute angiotensin-induced hypertensive rats

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelial cell dysfunction in homocystinuria

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The response-to-retention hypothesis of early atherogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Lipoproteins and the pathogenesis of atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

St Cyres lecture. Endothelium in control

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The molecular biology of platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Hypercholesterolemia increases endothelial superoxide anion production

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Oral L-arginine inhibits platelet aggregation but does not enhance endothelium-dependent dilation in healthy young men.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells: reversibility with oral L-arginine but not vitamin C.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolemia and is related to the lipoprotein(a) level

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Passive Smoking and Impaired Endothelium-Dependent Arterial Dilatation in Healthy Young Adults

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Preserved endothelium-dependent vasodilatation in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Hypertension associated with endothelin-secreting malignant hemangioendothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Early evidence of endothelial vasodilator dysfunction at coronary branch points

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Responses of coronary arteries of cardiac transplant patients to acetylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Paradoxical narrowing of atherosclerotic coronary arteries induced by increases in heart rate

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Endothelium-dependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Impaired endothelium-dependent vasodilation of coronary resistance vessels is associated with exercise-induced myocardial ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Constrictor and dilator responses to intracoronary acetylcholine in adjacent segments of the same coronary artery in patients with coronary artery disease. Endothelial function revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Reduction of transient myocardial ischemia with pravastatin in addition to the conventional treatment in patients with angina pectoris. REGRESS Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Effect of cholesterol reduction on myocardial ischemia in patients with coronary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Coronary angiographic changes with lovastatin therapy. The Monitored Atherosclerosis Regression Study (MARS).

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Restenosis after arterial angioplasty: A hemorrheologic response to injury

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolaemic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Effects of dietary L-arginine on atherosclerosis and endothelium-dependent vasodilatation in the hypercholesterolemic rabbit. Response according to treatment duration, anatomic site, and sex.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Reversing endothelial dysfunction with ACE inhibitors. A new trend

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Normalization of abnormal coronary vasomotion by calcium antagonists in patients with hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Hormone replacement therapy is associated with improved arterial physiology in healthy post-menopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2897%2900189-7

7 January 2021

10.1016/S0735-1097(97)00189-7

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

9247501