LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis (Q36889753)

16 August 2017

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis (English)

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16 August 2017

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Brian Estevez

1

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16 August 2017

Aleksandra Stojanovic-Terpo

2

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16 August 2017

M Keegan Delaney

3

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16 August 2017

Kelly A O'Brien

4

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16 August 2017

Michael C Berndt

5

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16 August 2017

Changgeng Ruan

6

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16 August 2017

Xiaoping Du

7

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16 August 2017

language of work or name

English

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publication date

25 April 2013

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16 August 2017

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16 August 2017

121

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16 August 2017

4586-4594

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16 August 2017

22

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3668491/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Signaling during platelet adhesion and activation

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von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

9 September 2017

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G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling

9 September 2017

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Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling

9 September 2017

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Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway

9 September 2017

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The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation

9 September 2017

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Adhesion mechanisms in platelet function

9 September 2017

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Signaling and regulation of the platelet glycoprotein Ib-IX-V complex

9 September 2017

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Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo

9 September 2017

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Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.

9 September 2017

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Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3

9 September 2017

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Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation

9 September 2017

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Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy

9 September 2017

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14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin

9 September 2017

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Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

9 September 2017

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Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model

9 September 2017

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Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2

9 September 2017

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Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

9 September 2017

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Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor

9 September 2017

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cPLA2 is phosphorylated and activated by MAP kinase

9 September 2017

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Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif

9 September 2017

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LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family

9 September 2017

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Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex

9 September 2017

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von Willebrand factor binding to platelet GpIb initiates signals for platelet activation

9 September 2017

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The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation

9 September 2017

1 reference

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Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice

27 June 2018

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A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications

27 June 2018

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The roles of ADP and TXA in botrocetin/VWF-induced aggregation of washed platelets

27 June 2018

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A stimulatory role for cGMP-dependent protein kinase in platelet activation

27 June 2018

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Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner

27 June 2018

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Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors.

4 September 2018

1 reference

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Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice.

4 September 2018

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A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.

4 September 2018

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Cytoskeletal regulation of the platelet glycoprotein Ib/V/IX-von willebrand factor interaction.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668491

The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668491

Aspirin ingestion compared with bleeding disorders--search for a useful platelet antiaggregant

4 September 2018

1 reference

12 December 2020

Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex

1 reference

12 December 2020

Thrombin-induced GPIb-IX centralization on the platelet surface requires actin assembly and myosin II activation

1 reference

12 December 2020

Hydrogen sulfide-releasing aspirin derivative ACS14 exerts strong antithrombotic effects in vitro and in vivo

1 reference

12 December 2020

Shear-dependent tether formation during platelet translocation on von Willebrand factor

1 reference

12 December 2020

A role for p38 MAP kinase in platelet activation by von Willebrand factor

1 reference

12 December 2020

Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia

1 reference

12 December 2020

10.1182/BLOOD-2012-12-470765

Identifiers

DOI

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16 August 2017

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16 August 2017

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