Sorafenib and sunitinib: novel targeted therapies for renal cell cancer (Q36892799)

16 August 2017

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title

Sorafenib and sunitinib: novel targeted therapies for renal cell cancer (English)

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16 August 2017

Cheryl A Grandinetti

1

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PubMed ID

17655513

16 August 2017

Barry R Goldspiel

series ordinal

2

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PubMed ID

17655513

16 August 2017

language of work or name

English

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publication date

1 August 2007

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16 August 2017

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16 August 2017

27

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16 August 2017

1125-1144

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16 August 2017

8

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16 August 2017

Cancer statistics, 2007

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Molecular genetics of familial renal cell carcinoma syndromes

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Novel treatment strategies in clear-cell metastatic renal cell carcinoma

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Raf kinase as a target for anticancer therapeutics

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Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

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Prognostic factors for survival of patients with stage IV renal cell carcinoma: memorial sloan-kettering cancer center experience.

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Cytokine therapy: a standard of care for metastatic renal cell carcinoma?

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

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Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma

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Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors

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Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors.

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Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours

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Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.

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Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics

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Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.

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Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects

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Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer

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Quantitation of SU1 1248, an oral multi-target tyrosine kinase inhibitor, and its metabolite in monkey tissues by liquid chromatograph with tandem mass spectrometry following semi-automated liquid-liquid extraction

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Sunitinib malate for the treatment of solid tumours: a review of current clinical data

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Sunitinib in patients with metastatic renal cell carcinoma

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

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Mechanisms of hypertension associated with BAY 43-9006.

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A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease

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Treatment of patients with metastatic renal cell cancer: a RAND Appropriateness Panel.

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Targeted agents for the treatment of advanced renal cell carcinoma

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Sorafenib: scientific rationales for single-agent and combination therapy in clear-cell renal cell carcinoma

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Adjuvant therapy for renal cell carcinoma

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Identifiers

DOI

10.1592/PHCO.27.8.1125

1 reference

16 August 2017

1 reference

PubMed ID

17655513