Molecular profiles of gastroenteropancreatic endocrine tumors. (Q36904566)

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3 January 2020

review article

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title

Molecular profiles of gastroenteropancreatic endocrine tumors (English)

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1

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3 January 2020

author name string

Martin Anlauf

series ordinal

2

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3 January 2020

Paul Komminoth

series ordinal

3

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publication date

8 August 2007

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3 January 2020

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3 January 2020

volume

451 Suppl 1

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3 January 2020

issue

S1

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28 June 2019

page(s)

S39-46

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https://scigraph.springernature.com/pub.10.1007/s00428-007-0449-9

3 January 2020

exact match

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cites work

Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumors

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Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms

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Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells

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Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization

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Genomic alterations in well-differentiated gastrointestinal and bronchial neuroendocrine tumors (carcinoids): marked differences indicating diversity in molecular pathogenesis

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Molecular parameters associated with insulinoma progression: chromosomal instability versus p53 and CK19 status

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12 December 2020

The presence of K-12 ras mutations in duodenal adenocarcinomas and the absence of ras mutations in other small bowel adenocarcinomas and carcinoid tumors

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Novel candidate tumour suppressor gene loci on chromosomes 11q23-24 and 22q13 involved in human insulinoma tumourigenesis

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BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors

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Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors

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Mutation of the MENIN gene in sporadic pancreatic endocrine tumors.

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Carcinoid tumors frequently display genetic abnormalities involving chromosome 11

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Accumulation of beta-catenin protein and mutations in exon 3 of beta-catenin gene in gastrointestinal carcinoid tumor.

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Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway

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Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas

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Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors

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BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors

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Nuclear translocation of beta-catenin protein but absence of beta-catenin and APC mutation in gastrointestinal carcinoid tumor.

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RET proto-oncogene point mutations in sporadic neuroendocrine tumors

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Oncogene expression in gastroenteropancreatic neuroendocrine tumors: implications for pathogenesis

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Comparative genomic hybridization analysis of sporadic neuroendocrine tumors of the digestive system

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Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets

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CpG island methylation in carcinoid and pancreatic endocrine tumors

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Chromosomal alterations in human pancreatic endocrine tumors

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Genomic imbalances in the progression of endocrine pancreatic tumors

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Survey of genetic alterations in gastrinomas

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Genetic alterations on 3p, 11q13, and 18q in nonfamilial and MEN 1-associated pancreatic endocrine tumors

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Molecular pathology of pancreatic cancer

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Identification of potential therapeutic targets by gene-expression profiling in pancreatic endocrine tumors

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Frequent overexpression of cyclin D1 in sporadic pancreatic endocrine tumours

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Pancreatic endocrine tumours: evidence for a tumour suppressor pathogenesis and for a tumour suppressor gene on chromosome 17p

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Somatic mutations of multiple endocrine neoplasia type 1 gene in the sporadic endocrine tumors

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Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients

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Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms

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Different patterns of 11q allelic losses in digestive endocrine tumors

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Alterations in the p16INK4a/CDKN2A tumor suppressor gene in gastrinomas

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Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9Q34 is an early event in insulinomas

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Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis

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Mutational analysis of Smad3, a candidate tumor suppressor implicated in TGF-beta and menin pathways, in parathyroid adenomas and enteropancreatic endocrine tumors

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Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system.

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Lack of MEN1 gene mutations in 27 sporadic insulinomas

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Comparison of mutations of ras oncogene in human pancreatic exocrine and endocrine tumors

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12 December 2020

DPC4/Smad4: no mutations, rare allelic imbalances, and retained protein expression in pancreatic endocrine tumors

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12 December 2020

Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas

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12 December 2020

Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumors of the endocrine pancreas

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12 December 2020

Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.

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12 December 2020

Oncogene expression in endocrine pancreatic tumors

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12 December 2020

A novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications

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Non-islet origin of pancreatic islet cell tumors.

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K-ras and p53 mutations in the pathogenesis of classical and goblet cell carcinoids of the appendix

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12 December 2020

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12 December 2020

Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progression

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12 December 2020

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12 December 2020

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12 December 2020

The multiple endocrine neoplasia type I gene locus is involved in the pathogenesis of type II gastric carcinoids

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12 December 2020

Chromosome 18 deletions are common events in classical midgut carcinoid tumors

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12 December 2020

Role of disease-causing genes in sporadic pancreatic endocrine tumors:MEN1andVHL

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12 December 2020

Endocrine tumors of the digestive tract and pancreas: histogenesis, diagnosis and molecular basis

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12 December 2020

10.1007/S00428-007-0449-9

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684763%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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