Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer (Q36906346)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

1 reference

head and neck carcinoma

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

16

Fred R Hirsch

1 reference

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28 February 2020

author name string

Stephen B Keysar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Phuong N Le

2

1 reference

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28 February 2020

Ryan T Anderson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

J Jason Morton

4

1 reference

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28 February 2020

Daniel W Bowles

5

1 reference

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28 February 2020

Jeramiah J Paylor

6

1 reference

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28 February 2020

Jackie Thorburn

8

1 reference

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28 February 2020

Pamela Fernandez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Magdalena J Glogowska

10

1 reference

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28 February 2020

Sarah M Takimoto

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Daniel B Sehrt

12

1 reference

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28 February 2020

Gregory N Gan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Justin R Eagles-Soukup

14

1 reference

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28 February 2020

Hilary Serracino

15

1 reference

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28 February 2020

M Scott Lucia

17

1 reference

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28 February 2020

Andrew Thorburn

18

1 reference

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28 February 2020

John I Song

19

1 reference

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28 February 2020

Xiao-Jing Wang

20

1 reference

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28 February 2020

Antonio Jimeno

21

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

10 April 2013

1 reference

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

73

1 reference

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28 February 2020

issue

11

1 reference

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28 February 2020

page(s)

3381-3392

1 reference

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Patient-derived tumour xenografts as models for oncology drug development

28 February 2020

cites work

1 reference

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Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway

29 September 2017

1 reference

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29 September 2017

Cancer statistics, 2012

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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model

29 September 2017

1 reference

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Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin

29 September 2017

1 reference

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Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

29 September 2017

1 reference

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The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

29 September 2017

1 reference

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Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)

29 September 2017

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The basics of epithelial-mesenchymal transition

29 September 2017

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

29 September 2017

1 reference

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Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus

29 September 2017

1 reference

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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

29 September 2017

1 reference

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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

29 September 2017

1 reference

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Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells.

29 September 2017

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Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers

29 September 2017

1 reference

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Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers

29 September 2017

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Platinum-based chemotherapy plus cetuximab in head and neck cancer

29 September 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

29 September 2017

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Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

29 September 2017

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Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674118

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

29 September 2017

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Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

29 September 2017

1 reference

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Gli1 acts through Snail and E-cadherin to promote nuclear signaling by beta-catenin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674118

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674118

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

29 September 2017

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Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

29 September 2017

1 reference

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29 September 2017

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29 September 2017

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29 September 2017

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

27 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23576557

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of apoptosis-related genes in human head and neck squamous cell carcinomas undergoing p53-mediated programmed cell death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23576557

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-12-4047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576557%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

23576557

1 reference