Pyrvinium targets autophagy addiction to promote cancer cell death (Q36907076)

17 August 2017

Pyrvinium targets autophagy addiction to promote cancer cell death (English)

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17 August 2017

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Longfei Deng

1

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17 August 2017

Yunlong Lei

2

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17 August 2017

Rui Liu

3

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17 August 2017

Jingyi Li

4

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17 August 2017

Kefei Yuan

5

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17 August 2017

Yi Li

6

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17 August 2017

Yi Chen

7

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17 August 2017

Yi Liu

8

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17 August 2017

You Lu

9

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17 August 2017

Carl K Edwards

10

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17 August 2017

Canhua Huang

11

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17 August 2017

Yuquan Wei

12

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17 August 2017

2 May 2013

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17 August 2017

Cell Death and Disease

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17 August 2017

4

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17 August 2017

e614

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3674351/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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29 September 2017

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Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages

29 September 2017

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Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT3.

29 September 2017

1 reference

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Targeting autophagy addiction in cancer

29 September 2017

1 reference

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29 September 2017

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Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

29 September 2017

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29 September 2017

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Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells

29 September 2017

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Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling

29 September 2017

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Autophagy as a target for anticancer therapy

29 September 2017

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Elevated inflammatory response in caveolin-1-deficient mice with Pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB)

29 September 2017

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Principles and current strategies for targeting autophagy for cancer treatment

29 September 2017

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

29 September 2017

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Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

29 September 2017

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Network organization of the human autophagy system

29 September 2017

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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

29 September 2017

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Discovery of Atg5/Atg7-independent alternative macroautophagy

29 September 2017

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Non-competitive androgen receptor inhibition in vitro and in vivo.

29 September 2017

1 reference

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Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy

29 September 2017

1 reference

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Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy

29 September 2017

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Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway

29 September 2017

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Efficacy of pyrvinium pamoate against Cryptosporidium parvum infection in vitro and in a neonatal mouse model

29 September 2017

1 reference

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E2F1 regulates autophagy and the transcription of autophagy genes

29 September 2017

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How to interpret LC3 immunoblotting

29 September 2017

1 reference

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674351

The role of autophagy during the early neonatal starvation period

29 September 2017

1 reference

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Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvation

29 September 2017

1 reference

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Autophagy as a regulated pathway of cellular degradation

29 September 2017

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

29 September 2017

1 reference

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Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

29 September 2017

1 reference

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Ammonium chloride, an inhibitor of phagosome-lysosome fusion in macrophages, concurrently induces phagosome-endosome fusion, and opens a novel pathway: studies of a pathogenic mycobacterium and a nonpathogenic yeast

29 September 2017

1 reference

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Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

29 September 2017

1 reference

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Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription.

27 June 2018

1 reference

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AMPK and Raptor: matching cell growth to energy supply.

4 September 2018

1 reference

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674351

An anticancer agent, pyrvinium pamoate inhibits the NADH–fumarate reductase system—a unique mitochondrial energy metabolism in tumour microenvironments

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2013.142

Inducing indigestion: companies embrace autophagy inhibitors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23640456

12 December 2020

inferred from PubMed ID database lookup

DNA fluorescence induced by polymethine cation pyrvinium binding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23640456

12 December 2020

inferred from PubMed ID database lookup

Animal responses to 2-deoxy-D-glucose administration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23640456

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/CDDIS.2013.142

1 reference

17 August 2017

1 reference

17 August 2017

1 reference