Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis (Q36913748)

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scientific article published on 17 May 2013

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English	Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis	scientific article published on 17 May 2013

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scholarly article

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Europe PubMed Central

17 August 2017

Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis (English)

1 reference

Europe PubMed Central

17 August 2017

1 reference

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author name string

Jin Yao

1

1 reference

Europe PubMed Central

17 August 2017

Hui-E Bi

2

1 reference

Europe PubMed Central

17 August 2017

Yi Sheng

3

1 reference

Europe PubMed Central

17 August 2017

Li-Bo Cheng

4

1 reference

Europe PubMed Central

17 August 2017

Ri-Le Wendu

5

1 reference

Europe PubMed Central

17 August 2017

Cheng-Hu Wang

6

1 reference

Europe PubMed Central

17 August 2017

Guo-Fan Cao

7

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Europe PubMed Central

17 August 2017

Qin Jiang

8

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Europe PubMed Central

17 August 2017

language of work or name

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publication date

17 May 2013

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Europe PubMed Central

17 August 2017

International Journal of Molecular Sciences

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Europe PubMed Central

17 August 2017

14

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Europe PubMed Central

17 August 2017

5

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Europe PubMed Central

17 August 2017

10355-10368

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Europe PubMed Central

17 August 2017

copyright license

Creative Commons Attribution 4.0 International

17 May 2013

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April 2022 Public Data File from Crossref

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3676843/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

AMP-activated protein kinase, stress responses and cardiovascular diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo

1 reference

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29 September 2017

Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition

1 reference

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Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors

1 reference

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Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

1 reference

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29 September 2017

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

1 reference

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Targeting the endoplasmic reticulum-stress response as an anticancer strategy

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ER-Golgi network--a future target for anti-cancer therapy

1 reference

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29 September 2017

AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes

1 reference

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29 September 2017

MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells

1 reference

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29 September 2017

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

1 reference

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

1 reference

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29 September 2017

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).

1 reference

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Prevalence of age-related macular degeneration in the United States

1 reference

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29 September 2017

A randomised controlled trial investigating the effect of nutritional supplementation on visual function in normal, and age-related macular disease affected eyes: design and methodology [ISRCTN78467674]

1 reference

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29 September 2017

Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

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29 September 2017

Ceramide: an intracellular signal for apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Solar radiation and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

29 September 2017

Protein, lipid and DNA repair systems in oxidative stress: the free-radical theory of aging revisited

1 reference

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29 September 2017

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme

1 reference

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27 June 2018

Targeting AMPK in the treatment of malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

4 September 2018

AMPK and Raptor: matching cell growth to energy supply.

1 reference

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4 September 2018

Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

4 September 2018

H2O2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676843

4 September 2018

Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23685869

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based on heuristic

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Perifosine sensitizes UVB-induced apoptosis in skin cells: new implication of skin cancer prevention?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23685869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23685869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2, Bax, and c-Fos expression correlates to RPE cell apoptosis induced by UV-light and daunorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23685869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/23685869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/IJMS140510355

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Europe PubMed Central

17 August 2017

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Europe PubMed Central

17 August 2017

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Europe PubMed Central

17 August 2017

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