The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization. (Q36915584)

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scientific article published on 21 May 2013

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English	The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.	scientific article published on 21 May 2013

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scholarly article

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1 March 2020

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization (English)

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1 March 2020

Faith H Brennan

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1 March 2020

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1 March 2020

Susanna Mantovani

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1 March 2020

Marc J. Ruitenberg

7

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1 March 2020

Trent M. Woodruff

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1 March 2020

author name string

Mike C L Wu

1

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1 March 2020

Rick A Wetsel

6

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1 March 2020

Stephen M Taylor

8

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1 March 2020

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21 May 2013

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1 March 2020

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6

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Proceedings of the National Academy of Sciences of the United States of America

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1 March 2020

110

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1 March 2020

23

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1 March 2020

9439-9444

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1 March 2020

De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation

1 reference

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29 September 2017

Inhibiting the C5-C5a receptor axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

Role of the complement components C5 and C3a in a mouse model of myocardial ischemia and reperfusion injury

1 reference

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29 September 2017

Human intestinal ischemia-reperfusion-induced inflammation characterized: experiences from a new translational model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

The role of the anaphylatoxins in health and disease

1 reference

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29 September 2017

Complement-mediated ischemia-reperfusion injury: lessons learned from animal and clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions

1 reference

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29 September 2017

Neutrophil mobilization and clearance in the bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

Elimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.

1 reference

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29 September 2017

Complement-targeted therapeutics

1 reference

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29 September 2017

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

The C3a receptor antagonist SB 290157 has agonist activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

The role of the complement system in ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

Sustained polymorphonuclear leukocyte transmigration induces apoptosis in T84 intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

The human C3a receptor is expressed on neutrophils and monocytes, but not on B or T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a stimulation of neutrophils is secondary to eosinophil activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

29 September 2017

Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion

1 reference

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29 September 2017

Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.

1 reference

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27 June 2018

Designing synthetic superagonists of C3a anaphylatoxin

1 reference

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27 June 2018

Synergy between proinflammatory ligands of G protein-coupled receptors in neutrophil activation and migration.

1 reference

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4 September 2018

Mouse bone marrow contains large numbers of functionally competent neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

4 September 2018

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677481

4 September 2018

Acute mesenteric ischemia after cardiopulmonary bypass

1 reference

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4 September 2018

C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury☆,☆☆

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218815110

21 January 2018

Diagnostic experiences with the naphthol AS-D chloroacetate esterase reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

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In vivo effects of C3a on neutrophils and its contribution to inflammatory lung processes in a guinea-pig model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

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Ischemia/reperfusion-induced feline intestinal dysfunction: importance of granulocyte recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement fragment C3a stimulates Ca2+ influx in neutrophils via a pertussis-toxin-sensitive G protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

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Degranulation from human eosinophils stimulated with C3a and C5a

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

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Complement peptides C3a- and C5a-induced mediator release from dissociated human skin mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

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Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

based on heuristic

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Successful selective thrombolysis for limb-threatening ischemia due to bilateral lower extremity emboli after open aortic aneurysm repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

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Bone marrow chimeric mice reveal a role for CX3 CR1 in maintenance of the monocyte-derived cell population in the olfactory neuroepithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

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Xanthine oxidase and neutrophil infiltration in intestinal ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696668

12 December 2020

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Identifiers

10.1073/PNAS.1218815110

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1 March 2020

2013PNAS..110.9439W

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1 March 2020

1 reference

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1 March 2020

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