Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity (Q36915859)

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scientific article published on 21 May 2008

Language	Label	Description	Also known as
English	Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity	scientific article published on 21 May 2008

Statements

scholarly article

1 reference

Europe PubMed Central

17 August 2017

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity (English)

1 reference

Europe PubMed Central

17 August 2017

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Coagulation factor VIII

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author name string

Qizhen Shi

1

1 reference

Europe PubMed Central

17 August 2017

Scot A Fahs

2

1 reference

Europe PubMed Central

17 August 2017

David A Wilcox

3

1 reference

Europe PubMed Central

17 August 2017

Erin L Kuether

4

1 reference

Europe PubMed Central

17 August 2017

Patricia A Morateck

5

1 reference

Europe PubMed Central

17 August 2017

Nicole Mareno

6

1 reference

Europe PubMed Central

17 August 2017

Hartmut Weiler

7

1 reference

Europe PubMed Central

17 August 2017

Robert R Montgomery

8

1 reference

Europe PubMed Central

17 August 2017

language of work or name

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publication date

21 May 2008

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

112

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Europe PubMed Central

17 August 2017

7

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Europe PubMed Central

17 August 2017

2713-2721

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Europe PubMed Central

17 August 2017

Surgical interventions in a cohort of patients with haemophilia A and inhibitors: an experiential retrospective chart review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Hematopoietic stem-cell gene therapy of hemophilia A incorporating a porcine factor VIII transgene and nonmyeloablative conditioning regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

An overview of the history, clinical practice concerns, comparative studies and strategies to optimize therapy of bypassing agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current European practice in immune tolerance induction therapy in patients with haemophilia and inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current and future approaches to inhibitor management and aversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Correction of murine hemophilia A by hematopoietic stem cell gene therapy

1 reference

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29 September 2017

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

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29 September 2017

Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Inhibitors in congenital coagulation disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Pathogenic antibodies to coagulation factors. Part one: factor VIII and factor IX.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Inhibitors in hemophilia A: mechanisms of inhibition, management and perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Recombinant factor VIII expression in hematopoietic cells following lentiviral transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Immune tolerance induction in patients with haemophilia A with inhibitors: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Haemophilias A and B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

High level expression of human factor VIII in mammalian cells after retroviral-mediated gene transfer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Hemophilia. Strategies for the treatment of inhibitor patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Properties of anti-factor VIII inhibitor antibodies in hemophilia A patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Advances toward gene therapy for hemophilia at the millennium

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Biosynthesis, assembly and secretion of coagulation factor VIII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Intracellular trafficking of factor VIII to von Willebrand factor storage granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

A practical guide to the evaluation and treatment of hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current use of by-passing agents in Europe in the management of acute bleeds in patients with haemophilia and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Immune tolerance induction in the treatment of paediatric haemophilia A patients with factor VIII inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Humoral immunity due to long-lived plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Effects of irradiation on the in vitro immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

High expression reduces an antibody response after neonatal gene therapy with B domain-deleted human factor VIII in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Hematopoietic stem cells encoding porcine factor VIII induce pro-coagulant activity in hemophilia A mice with pre-existing factor VIII immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Efficient AAV1-AAV2 hybrid vector for gene therapy of hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Acquired factor VIII inhibitor in a non-haemophilic boy.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Efficient production of human FVIII in hemophilic mice using lentiviral vectors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

The abrogation of allosensitization following the induction of mixed allogeneic chimerism.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Reaginic antibody formation in the mouse. XI. Participation of long-lived antibody-forming cells in persistent antibody formation.

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4 September 2018

Two phases of engraftment established by serial bone marrow transplantation in mice.

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4 September 2018

Synthesis of antibody by spleen cells after exposure to kiloroentgen doses of ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

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The Nijmegen modification of the Bethesda assay for factor VIII:C inhibitors: improved specificity and reliability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiosensitivity of spleen cells from normal and preimmunized mice and its significance to intact animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2008-02-138214

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

ResearchGate publication ID

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