eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling (Q36920075)

17 August 2017

eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling (English)

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17 August 2017

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Funda Meric-Bernstam

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17 August 2017

Ana Maria Gonzalez-Angulo

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object named as

Ana Gonzalez-Angulo

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17 August 2017

Alpana Soni

1

1 reference

17 August 2017

Argun Akcakanat

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17 August 2017

Gopal Singh

3

1 reference

17 August 2017

David Luyimbazi

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17 August 2017

Yuhuan Zheng

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17 August 2017

Doyil Kim

6

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17 August 2017

1 July 2008

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Molecular Cancer Therapeutics

17 August 2017

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7

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17 August 2017

1782-1788

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17 August 2017

7

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2559956/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

29 September 2017

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Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

29 September 2017

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Expression levels of eIF4E, VEGF, and cyclin D1, and correlation of eIF4E with VEGF and cyclin D1 in multi-tumor tissue microarray

29 September 2017

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29 September 2017

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

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hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation

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Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

29 September 2017

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Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

29 September 2017

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eIF-4E expression and its role in malignancies and metastases.

29 September 2017

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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

29 September 2017

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Determinants of rapamycin sensitivity in breast cancer cells

29 September 2017

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mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

29 September 2017

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Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release.

29 September 2017

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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

29 September 2017

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Hierarchical phosphorylation of the translation inhibitor 4E-BP1

29 September 2017

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Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis

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Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

29 September 2017

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29 September 2017

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Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology

29 September 2017

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29 September 2017

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mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E

29 September 2017

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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

29 September 2017

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Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency.

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Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells

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The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

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Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma

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12 December 2020

Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas

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12 December 2020

Embryonic-stage-dependent changes in the level of eIF4E-binding proteins during early development of sea urchin embryos

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12 December 2020

High eIF4E, VEGF, and microvessel density in stage I to III breast cancer

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12 December 2020

10.1158/1535-7163.MCT-07-2357

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

1 reference