Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer (Q36922264)

17 August 2017

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title

Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer (English)

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17 August 2017

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Myxoma virus

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2

Grant McFadden

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17 August 2017

Marianne M Stanford

1

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PubMed ID

17727330

17 August 2017

language of work or name

English

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publication date

1 September 2007

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Expert Opinion on Biological Therapy

17 August 2017

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17 August 2017

7

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17 August 2017

9

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17 August 2017

1415-1425

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Stem cell collection and gene transfer in Fanconi anemia

17 August 2017

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Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress

21 January 2018

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Recent clinical progress in virus-based therapies for cancer.

21 January 2018

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Fighting cancer with oncolytic viruses

21 January 2018

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The use of oncolytic vaccinia viruses in the treatment of cancer: a new role for an old ally?

21 January 2018

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Immunopathogenesis of poxvirus infections: forecasting the impending storm

21 January 2018

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Varicella-zoster virus requires a functional PI3K/Akt/GSK-3alpha/beta signaling cascade for efficient replication

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Biochemical aspects of coronavirus replication and virus-host interaction.

21 January 2018

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Extensive syncytium formation mediated by the reovirus FAST proteins triggers apoptosis-induced membrane instability

21 January 2018

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Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death

21 January 2018

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Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

21 January 2018

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The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

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TOR, a central controller of cell growth

21 January 2018

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Oncolytic viruses: what's next?

21 January 2018

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Oncolytic virus therapy--foreword

21 January 2018

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Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer

21 January 2018

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

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Elucidation of the molecular mechanism underlying tumor-selective replication of the oncolytic adenovirus mutant ONYX-015.

21 January 2018

1 reference

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Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

21 January 2018

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Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

21 January 2018

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Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

21 January 2018

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China approves world's first oncolytic virus therapy for cancer treatment

21 January 2018

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Systemic efficacy with oncolytic virus therapeutics: clinical proof-of-concept and future directions.

21 January 2018

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Oncolytic viral therapies - the clinical experience

21 January 2018

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Getting oncolytic virus therapies off the ground

21 January 2018

1 reference

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Fighting cancer with vaccinia virus: teaching new tricks to an old dog.

21 January 2018

1 reference

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Vaccinia as a vector for tumor-directed gene therapy: biodistribution of a thymidine kinase-deleted mutant

21 January 2018

1 reference

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Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates

21 January 2018

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Development of a replication-selective, oncolytic poxvirus for the treatment of human cancers

21 January 2018

1 reference

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Cell proliferative response to vaccinia virus is mediated by VGF.

21 January 2018

1 reference

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Vaccinia as a vector for gene delivery

21 January 2018

1 reference

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The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2.

21 January 2018

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A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virus

21 January 2018

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Virotherapy clinical trials for regional disease: in situ immune modulation using recombinant poxvirus vectors

21 January 2018

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Intralesional vaccinia/GM-CSF recombinant virus in the treatment of metastatic melanoma

21 January 2018

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Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma

21 January 2018

1 reference

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Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF.

21 January 2018

1 reference

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Yaba-like disease virus: an alternative replicating poxvirus vector for cancer gene therapy

21 January 2018

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Virology- and immunology-based gene therapy for cancer.

21 January 2018

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The potential role of fowlpox virus in rational vaccine design

21 January 2018

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Development of the PANVAC-VF vaccine for pancreatic cancer

21 January 2018

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Fowlpox virus as a recombinant vaccine vector for use in mammals and poultry

21 January 2018

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Myxoma virus in the European rabbit: interactions between the virus and its susceptible host

21 January 2018

1 reference

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A pox on thee! Manipulation of the host immune system by myxoma virus and implications for viral-host co-adaptation

21 January 2018

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Immune responses to myxoma virus

21 January 2018

1 reference

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Immunomodulatory proteins of myxoma virus

21 January 2018

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Vaccination of cats with an attenuated recombinant myxoma virus expressing feline calicivirus capsid protein

21 January 2018

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21 January 2018

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Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier

21 January 2018

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Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas

21 January 2018

1 reference

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Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1

21 January 2018

1 reference

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Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor.

21 January 2018

1 reference

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Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

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Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01.

21 January 2018

1 reference

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Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy

21 January 2018

1 reference

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Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma

21 January 2018

1 reference

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Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

21 January 2018

1 reference

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From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy

21 January 2018

1 reference

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Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells

21 January 2018

1 reference

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Everolimus: a review of its use in renal and cardiac transplantation

21 January 2018

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Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis

21 January 2018

1 reference

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Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials

21 January 2018

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Technical knockout: understanding poxvirus pathogenesis by selectively deleting viral immunomodulatory genes

21 January 2018

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Secreted immunomodulatory viral proteins as novel biotherapeutics

21 January 2018

1 reference

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Serp-1, a viral anti-inflammatory serpin, regulates cellular serine proteinase and serpin responses to vascular injury

21 January 2018

1 reference

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Myxoma virus M-T7, a secreted homolog of the interferon-gamma receptor, is a critical virulence factor for the development of myxomatosis in European rabbits

21 January 2018

1 reference

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Chemokine-binding viral protein M-T7 prevents chronic rejection in rat renal allografts.

21 January 2018

1 reference

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The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury

21 January 2018

1 reference

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The T1/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues

21 January 2018

1 reference

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Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity.

21 January 2018

1 reference

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Strategies to achieve systemic delivery of therapeutic cells and microbes to tumors

21 January 2018

1 reference

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21 January 2018

Poxvirus cancer therapy

1 reference

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Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector

21 January 2018

1 reference

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Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice

21 January 2018

1 reference

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Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy

21 January 2018

1 reference

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PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

21 January 2018

1 reference

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10.1517/14712598.7.9.1415

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17727330