Switch of substrate specificity of hyperthermophilic acylaminoacyl peptidase by combination of protein and solvent engineering. (Q36922673)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21748600%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Switch of substrate specificity of hyperthermophilic acylaminoacyl peptidase by combination of protein and solvent engineering (English)

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7 February 2020

3

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7 February 2020

author name string

Chang Liu

1

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7 February 2020

Guangyu Yang

2

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7 February 2020

Guohe Tian

4

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7 February 2020

Zuoming Zhang

5

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7 February 2020

Yan Feng

6

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7 February 2020

publication date

1 June 2011

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7 February 2020

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7 February 2020

volume

2

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7 February 2020

issue

6

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7 February 2020

page(s)

497-506

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Distributions of enzyme residues yielding mutants with improved substrate specificities from two different directed evolution strategies

7 February 2020

cites work

1 reference

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Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms

29 September 2017

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Engineered enzymes for chemical production

29 September 2017

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Microbial lipases: at the interface of aqueous and non-aqueous media. A review.

29 September 2017

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Lipases from extremophiles and potential for industrial applications

29 September 2017

1 reference

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Enzyme promiscuity: mechanism and applications.

29 September 2017

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Alicyclobacillus acidocaldarius thermophilic esterase EST2's activity in milk and cheese models.

29 September 2017

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29 September 2017

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Improving enzyme properties: when are closer mutations better?

29 September 2017

1 reference

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The 'evolvability' of promiscuous protein functions

29 September 2017

1 reference

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Lipases and their industrial applications: an overview

29 September 2017

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An efficient one-step site-directed and site-saturation mutagenesis protocol

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Hydration of enzyme in nonaqueous media is consistent with solvent dependence of its activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Saturation mutagenesis of toluene ortho-monooxygenase of Burkholderia cepacia G4 for Enhanced 1-naphthol synthesis and chloroform degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Protein structure and dynamics in nonaqueous solvents: insights from molecular dynamics simulation studies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Catalyzing "hot" reactions: enzymes from hyperthermophilic Archaea

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Simulating pseudogene evolution in vitro: determining the true number of mutations in a lineage.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Comparative protein structure modeling of genes and genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Extremophiles as a source of novel enzymes for industrial application

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Catalytic promiscuity and the evolution of new enzymatic activities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Enzyme-catalyzed processes in organic solvents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Assessment of protein models with three-dimensional profiles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

PACKMOL: a package for building initial configurations for molecular dynamics simulations.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Glu88 in the non-catalytic domain of acylpeptide hydrolase plays dual roles: charge neutralization for enzymatic activity and formation of salt bridge for thermodynamic stability

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875176

PROCHECK: a program to check the stereochemical quality of protein structures

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS13238-011-1057-7

HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21748600

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13238-011-1057-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21748600%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21748600%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

21748600

1 reference