Autoimmunity: IL-21: a new player in Th17-cell differentiation (Q36927989)

17 August 2017

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title

Autoimmunity: IL-21: a new player in Th17-cell differentiation. (English)

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17 August 2017

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Elissa K Deenick

1

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PubMed ID

17768419

17 August 2017

Stuart G Tangye

series ordinal

2

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17 August 2017

4 September 2007

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Immunology & Cell Biology

17 August 2017

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17 August 2017

85

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17 August 2017

7

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17 August 2017

503-505

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Transforming growth factor-beta induces development of the T(H)17 lineage

17 August 2017

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-17 family cytokines and the expanding diversity of effector T cell lineages

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Follicular B helper T cells in antibody responses and autoimmunity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Common variable immunodeficiency: The power of co-stimulation.

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Phenotypic and functional features of human Th17 cells

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100114

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100114

1 reference

17 August 2017

1 reference

PubMed ID

17768419