The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy (Q36933316)

17 August 2017

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title

The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy (English)

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17 August 2017

2

Roger F Butterworth

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17 August 2017

Samir Ahboucha

1

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17 August 2017

publication date

1 December 2007

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17 August 2017

published in

Metabolic Brain Disease

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17 August 2017

volume

22

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17 August 2017

issue

3-4

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17 August 2017

page(s)

291-308

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The effect of liver transplantation on circulating levels of estradiol and progesterone in male patients: parallelism with hepatopulmonary syndrome and systemic hyperdynamic circulation improvement.

17 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS11011-007-9065-2

Acute liver failure and hyperammonemia increase peripheral-type benzodiazepine receptor binding and pregnenolone synthesis in mouse brain

21 January 2018

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12 December 2020

Flumazenil vs. placebo in hepatic encephalopathy in patients with cirrhosis: a meta-analysis

1 reference

12 December 2020

Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction

1 reference

12 December 2020

Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure

1 reference

12 December 2020

Alterations in expression of genes coding for key astrocytic proteins in acute liver failure

1 reference

12 December 2020

Improvement in cholestasis-associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment

1 reference

12 December 2020

Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy

1 reference

12 December 2020

Monoamine oxidase-A is a major target gene for glucocorticoids in human skeletal muscle cells.

1 reference

12 December 2020

Potential mechanisms of enhanced GABA-mediated inhibitory neurotransmission in liver failure

1 reference

12 December 2020

Immunohistochemistry of diazepam binding inhibitor (DBI) in the central nervous system and peripheral organs: its possible role as an endogenous regulator of different types of benzodiazepine receptors.

1 reference

12 December 2020

Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats

1 reference

12 December 2020

Serotonin 5-HT(3) receptors in the central nervous system

1 reference

12 December 2020

Peripheral benzodiazepine receptors and mitochondrial function

1 reference

12 December 2020

Extraadrenal steroid 21-hydroxylation is not mediated by P450c21

1 reference

12 December 2020

Relief from profound fatigue associated with chronic liver disease by long-term ondansetron therapy

1 reference

12 December 2020

Increased densities of binding sites for the peripheral-type benzodiazepine receptor ligand [3H]PK 11195 in congenital ornithine transcarbamylase-deficient sparse fur mouse

1 reference

12 December 2020

Affinities and densities of high-affinity [3H]muscimol (GABA-A) binding sites and of central benzodiazepine receptors are unchanged in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy.

1 reference

12 December 2020

Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes

1 reference

12 December 2020

Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.

1 reference

12 December 2020

Neurosteroids: biochemistry and clinical significance

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12 December 2020

Increased brain content of the endogenous benzodiazepine receptor ligand, octadecaneuropeptide (ODN), following portacaval anastomosis in the rat.

1 reference

12 December 2020

The hyperventilation of cirrhosis: progesterone and estradiol effects.

1 reference

12 December 2020

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

12 December 2020

Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats

1 reference

12 December 2020

Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.

1 reference

12 December 2020

Ammonia-induced upregulation of peripheral-type benzodiazepine receptors in cultured astrocytes labeled with [3H]PK 11195

1 reference

12 December 2020

Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex

1 reference

12 December 2020

Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy

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12 December 2020

Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis

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12 December 2020

The role of astrocytes in hepatic encephalopathy

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12 December 2020

Brain monoamine output alterations after a single venlafaxine challenge in experimental hepatic encephalopathy.

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12 December 2020

The neuropsychopharmacological potential of neuroactive steroids

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12 December 2020

Reversal of hepatic coma by benzodiazepine antagonist (Ro 15-1788)

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12 December 2020

All progestins are not created equal

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12 December 2020

Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats.

1 reference

12 December 2020

Induction of peripheral-type benzodiazepine receptors in mouse brain following thioacetamide-induced acute liver failure

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12 December 2020

Fatigue and primary biliary cirrhosis: association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels.

1 reference

12 December 2020

Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain

1 reference

12 December 2020

Octadecaneuropeptide (ODN; 'anxiety peptide') displaces diazepam more potently from astrocytic than from neuronal binding sites.

1 reference

12 December 2020

In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy

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12 December 2020

Cerebrospinal fluid content of diazepam binding inhibitor in chronic hepatic encephalopathy.

1 reference

12 December 2020

Increased densities of peripheral-type benzodiazepine receptors in brain autopsy samples from cirrhotic patients with hepatic encephalopathy.

1 reference

12 December 2020

Vascular differentiation and glucose transporter expression in rat gliomas: effects of steroids

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12 December 2020

Increased densities of binding sites for the 'peripheral-type' benzodiazepine receptor ligand [3H]PK 11195 in rat brain following portacaval anastomosis

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12 December 2020

Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: effect of cirrhosis of the liver

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12 December 2020

Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives

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12 December 2020

Alterations of neurotransmitter-related gene expression in human and experimental portal-systemic encephalopathy

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12 December 2020

Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

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12 December 2020

Corticosteroid effects on gene expression of myelin basic protein in oligodendrocytes and of glial fibrillary acidic protein in type 1 astrocytes.

1 reference

12 December 2020

Chronic exposure of rat primary astrocyte cultures to manganese results in increased binding sites for the 'peripheral-type' benzodiazepine receptor ligand 3H-PK 11195.

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12 December 2020

Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat.

1 reference

12 December 2020

Modulation of hepatic encephalopathy in rats with thioacetamide-induced acute liver failure by serotonin antagonists.

1 reference

12 December 2020

Upregulation of 'peripheral-type' benzodiazepine receptors in the globus pallidus in a sub-acute rat model of manganese neurotoxicity

1 reference

12 December 2020

Diazepam binding inhibitor (DBI): a peptide with multiple biological actions

1 reference

12 December 2020

Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment

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12 December 2020

Tissue-specific alterations of binding sites for peripheral-type benzodiazepine receptor ligand [3H]PK11195 in rats following portacaval anastomosis

1 reference

12 December 2020

Fatigue of cholestasis and the serotoninergic neurotransmitter system in the rat.

1 reference

12 December 2020

An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons

1 reference

12 December 2020

Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat.

1 reference

12 December 2020

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

1 reference

12 December 2020

Densities of binding sites for the "peripheral-type" benzodiazepine receptor ligand 3H-PK11195 are increased in brain 24 hours following portacaval anastomosis

1 reference

12 December 2020

Progesterone, prolactin, and gynaecomastia in men with liver disease

1 reference

12 December 2020

Diazepam binding inhibitor gene expression: location in brain and peripheral tissues of rat

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12 December 2020

The peripheral benzodiazepine receptor and neurosteroids in hepatic encephalopathy.

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12 December 2020

Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy

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12 December 2020

Modulation of neocortical interneurons: extrinsic influences and exercises in self-control

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12 December 2020

The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders

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12 December 2020

Portacaval anastomosis causes selective alterations of peripheral-type benzodiazepine receptor expression in rat brain and peripheral tissues

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12 December 2020

Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain

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12 December 2020

Hepatic encephalopathy: An update of pathophysiologic mechanisms

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12 December 2020

Neurosteroids: a novel function of the brain

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12 December 2020

Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo

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12 December 2020

Progesterone receptor-mediated effects of neuroactive steroids

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12 December 2020

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

1 reference

12 December 2020

Effect of ondansetron, a 5-HT3 receptor antagonist, on fatigue in chronic hepatitis C: a randomised, double blind, placebo controlled study

1 reference

12 December 2020

Modulation of ligand binding to components of the GABAA receptor complex by ammonia: implications for the pathogenesis of hyperammonemic syndromes

1 reference

12 December 2020

Altered open-field behavior in experimental chronic hepatic encephalopathy after single venlafaxine and citalopram challenges

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12 December 2020

10.1007/S11011-007-9065-2

Identifiers

DOI

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17 August 2017

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