Calcium, ageing, and neuronal vulnerability in Parkinson's disease (Q36947731)

17 August 2017

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title

Calcium, ageing, and neuronal vulnerability in Parkinson's disease (English)

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17 August 2017

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D James Surmeier

1

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17 August 2017

1 October 2007

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17 August 2017

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17 August 2017

6

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17 August 2017

10

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17 August 2017

933-938

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Parkinson's disease: mechanisms and models

17 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Parkinsonism: onset, progression, and mortality

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Neurodegeneration and neuroprotection in Parkinson disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Clinical trials for neuroprotection in Parkinson's disease: overcoming angst and futility?

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Stages in the development of Parkinson's disease-related pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Time course of nigrostriatal degeneration in parkinson's disease. A detailed study of influential factors in human brain amine analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Biomedicine. Parkinson's--divergent causes, convergent mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Calbindin-D28k in the basal ganglia of patients with parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Medullary catecholaminergic neurons in the normal human brain and in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Preservation of hypothalamic dopaminergic neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Molecular pathophysiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

GABAergic control of the firing pattern of substantia nigra dopaminergic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Responses of rat substantia nigra dopamine-containing neurones to (-)-HA-966 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Blockade of SK-type Ca2+-activated K+ channels uncovers a Ca2+-dependent slow afterdepolarization in nigral dopamine neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

L-Type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Role of voltage-gated L-type Ca2+ channel isoforms for brain function.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

G-protein-coupled receptor modulation of striatal CaV1.3 L-type Ca2+ channels is dependent on a Shank-binding domain.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Coupled oscillator model of the dopaminergic neuron of the substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Neuronal calcium signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

The biologic clock: the mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Histological changes of the dopaminergic nigrostriatal system in aging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Compensations after lesions of central dopaminergic neurons: some clinical and basic implications

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Origin and functional consequences of the complex I defect in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Inflammation as a causative factor in the aetiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Disease-specific patterns of locus coeruleus cell loss

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Membrane properties of rat locus coeruleus neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Space, time and dopamine.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

The control of firing pattern in nigral dopamine neurons: single spike firing

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Calcium channel blockers: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Calcium channel blockers and beta-blockers in relation to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

D2 receptor blockade by flunarizine and cinnarizine explains extrapyramidal side effects. A SPECT study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Can calcium antagonists provide a neuroprotective effect in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Isradipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Characteristics of orthostatic hypotension in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Post-receptor mechanisms underlying striatal long-term depression.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

Neuronal L-type calcium channels open quickly and are inhibited slowly

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970246-6

7 January 2021

10.1016/S1474-4422(07)70246-6

Identifiers

DOI

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17 August 2017

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PubMed ID

17884683