CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract. (Q36950621)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855710%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract (English)

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9 February 2020

main subject

Chlamydia trachomatis

0 references

author

Andrew Olive

series ordinal

2

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9 February 2020

Georg Stary

series ordinal

3

1 reference

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9 February 2020

4

Michael N Starnbach

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9 February 2020

author name string

David C Gondek

series ordinal

1

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9 February 2020

language of work or name

English

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publication date

1 August 2012

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9 February 2020

published in

Journal of Immunology

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9 February 2020

volume

189

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9 February 2020

issue

5

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9 February 2020

page(s)

2441-2449

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Identification of antigen-specific antibody responses associated with upper genital tract pathology in mice infected with Chlamydia muridarum

9 February 2020

cites work

1 reference

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Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection.

9 September 2017

1 reference

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Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections

9 September 2017

1 reference

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Approach to discover T- and B-cell antigens of intracellular pathogens applied to the design of Chlamydia trachomatis vaccines

9 September 2017

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Evaluation of a broadly protective Chlamydia-cholera combination vaccine candidate

9 September 2017

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Murine Chlamydia trachomatis genital infection is unaltered by depletion of CD4+ T cells and diminished adaptive immunity

9 September 2017

1 reference

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The female lower genital tract is a privileged compartment with IL-10 producing dendritic cells and poor Th1 immunity following Chlamydia trachomatis infection

9 September 2017

1 reference

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Vaccination against Chlamydia genital infection utilizing the murine C. muridarum model

9 September 2017

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CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa.

9 September 2017

1 reference

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Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract

9 September 2017

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Protective immunity to Chlamydia trachomatis genital infection: evidence from human studies

9 September 2017

1 reference

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Development of a Chlamydia trachomatis T cell Vaccine

9 September 2017

1 reference

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Protective immunity to chlamydial genital infection: evidence from animal studies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Plasmacytoid dendritic cells modulate nonprotective T-cell responses to genital infection by Chlamydia muridarum

9 September 2017

1 reference

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Role of T lymphocytes in the pathogenesis of Chlamydia disease

9 September 2017

1 reference

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T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Strain and virulence diversity in the mouse pathogen Chlamydia muridarum

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Two different homing pathways involving integrin β7 and E-selectin significantly influence trafficking of CD4 cells to the genital tract following Chlamydia muridarum infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Tracking epitope-specific T cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.

9 September 2017

1 reference

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T-cell quality in memory and protection: implications for vaccine design

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Identification of human T cell targets recognized during Chlamydia trachomatis genital infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Immune-mediated control of Chlamydia infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Differential CD28 and inducible costimulatory molecule signaling requirements for protective CD4+ T-cell-mediated immunity against genital tract Chlamydia trachomatis infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Antigen-specific CD8+ T cells respond to Chlamydia trachomatis in the genital mucosa

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Monitoring the T cell response to genital tract infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Chlamydia trachomatis persistence: an update

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Host inflammatory response and development of complications of Chlamydia trachomatis genital infection in CCR5-deficient mice and subfertile women with the CCR5delta32 gene deletion.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Chlamydial IFN-gamma immune evasion is linked to host infection tropism

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

The infecting dose of Chlamydia muridarum modulates the innate immune response and ascending infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

9 September 2017

1 reference

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Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-gamma-mediated inhibition

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Role of NK cells in early host response to chlamydial genital infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

B-cell-deficient mice develop complete immune protection against genital tract infection with Chlamydia trachomatis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Studies in knockout mice reveal that anti-chlamydial protection requires TH1 cells producing IFN-gamma: is this true for humans?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Murine cytotoxic T lymphocytes induced following Chlamydia trachomatis intraperitoneal or genital tract infection respond to cells infected with multiple serovars

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690950

9 September 2017

Identifiers

DOI

10.4049/JIMMUNOL.1103032

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855710%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855710%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

22855710

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855710%20AND%20SRC:MED&resulttype=core&format=json