Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells. (Q36953350)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18816109%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells (English)

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14 January 2020

1 reference

1

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14 January 2020

author name string

Vesna Milacic

series ordinal

2

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14 January 2020

Jan Taraba

series ordinal

3

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14 January 2020

Q Ping Dou

series ordinal

4

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14 January 2020

language of work or name

English

0 references

publication date

25 September 2008

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Journal of Medicinal Chemistry

14 January 2020

published in

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14 January 2020

volume

51

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14 January 2020

issue

20

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14 January 2020

page(s)

6256-6258

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The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?

14 January 2020

cites work

1 reference

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Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity

29 September 2017

1 reference

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

29 September 2017

1 reference

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Proteasome inhibitors in cancer therapy: lessons from the first decade

29 September 2017

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Targeting of nuclear factor-kappaB and proteasome by dithiocarbamate complexes with metals

29 September 2017

1 reference

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Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway.

29 September 2017

1 reference

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Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis

29 September 2017

1 reference

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Inhibition of the proteasome activity by gallium(III) complexes contributes to their anti prostate tumor effects

29 September 2017

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Modelling breast cancer: one size does not fit all.

29 September 2017

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A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation

29 September 2017

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29 September 2017

New uses for old drugs

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Role of peroxidases, thiols and Bak/Bax in tumor cell susceptibility to Cu[DEDTC]2.

29 September 2017

1 reference

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20S proteasome and its inhibitors: crystallographic knowledge for drug development

29 September 2017

1 reference

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The JAMM motif of human deubiquitinase Poh1 is essential for cell viability

29 September 2017

1 reference

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A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Anticancer metal compounds in NCI's tumor-screening database: putative mode of action

29 September 2017

1 reference

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Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

The origin of an EPR signal observed in dithiocarbamate-loaded tissues. Copper(II)-dithiocarbamate complexes account for the narrow hyperfine lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Characterization of an inhibitory metal binding site in carboxypeptidase A.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

27 June 2018

1 reference

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Synthesis, characterization, and comparative in vitro cytotoxicity studies of platinum(II), palladium(II), and gold(III) methylsarcosinedithiocarbamate complexes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574941

Bonding analyses, formation energies, and vibrational properties of M-R2dtc complexes (M=Ag(I), Ni(II), Cu(II), or Zn(II))

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18816109

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New uses for old copper-binding drugs: converting the pro-angiogenic copper to a specific cancer cell death inducer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18816109

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM8007807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18816109%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18816109%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18816109

1 reference