Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. (Q36955137)

17 August 2017

Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. (English)

1 reference

17 August 2017

Christian D Young

1

1 reference

17 August 2017

Erica C Nolte

2

1 reference

17 August 2017

Andrew Lewis

3

1 reference

17 August 2017

Natalie J Serkova

4

1 reference

17 August 2017

Steven M Anderson

5

1 reference

17 August 2017

13 August 2008

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17 August 2017

Breast Cancer Research

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17 August 2017

10

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17 August 2017

4

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17 August 2017

R70

1 reference

https://scigraph.springernature.com/pub.10.1186/bcr2132

17 August 2017

0 references

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Sugar and fat - that's where it's at: metabolic changes in tumors

29 September 2017

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ShcA signalling is essential for tumour progression in mouse models of human breast cancer

29 September 2017

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29 September 2017

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29 September 2017

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AKT/PKB signaling: navigating downstream

29 September 2017

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29 September 2017

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Akt1 governs breast cancer progression in vivo

29 September 2017

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c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function

29 September 2017

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29 September 2017

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The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells

29 September 2017

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29 September 2017

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Cancer-specific mutations in PIK3CA are oncogenic in vivo

29 September 2017

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29 September 2017

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ATP citrate lyase inhibition can suppress tumor cell growth

29 September 2017

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Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.

29 September 2017

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Living with or without cyclins and cyclin-dependent kinases

29 September 2017

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

29 September 2017

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Akt stimulates aerobic glycolysis in cancer cells

29 September 2017

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

29 September 2017

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On the Origin of Cancer Cells

29 September 2017

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

29 September 2017

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29 September 2017

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Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors

29 September 2017

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Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.

29 September 2017

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A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners

29 September 2017

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Tyrosine kinase signalling in breast cancer: tyrosine kinase-mediated signal transduction in transgenic mouse models of human breast cancer.

29 September 2017

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Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

29 September 2017

1 reference

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An atlas of mouse mammary gland development

29 September 2017

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The ErbB signaling network: receptor heterodimerization in development and cancer

29 September 2017

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Mammary gland neoplasia: insights from transgenic mouse models

29 September 2017

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The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

29 September 2017

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

29 September 2017

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

29 September 2017

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Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice

29 September 2017

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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

29 September 2017

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Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

29 September 2017

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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

29 September 2017

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Transport of sugars in tumor cell membranes

29 September 2017

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

29 September 2017

1 reference

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Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

29 September 2017

1 reference

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

29 September 2017

1 reference

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Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

Signal transduction: clamping down on Src activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

Activated neu induces rapid tumor progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

27 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

27 June 2018

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Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

21 January 2018

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Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine.

21 January 2018

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An essential role for Src kinase in ErbB receptor signaling through the MAPK pathway

21 January 2018

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Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

21 January 2018

1 reference

Mammary gland involution is delayed by activated Akt in transgenic mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575543

Molecular cloning and developmental expression of mouse p130, a member of the retinoblastoma gene family

4 September 2018

1 reference

Delayed mammary gland involution in MMTV-AKT1 transgenic mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18700973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Downregulation of erbB3 abrogates erbB2-mediated tamoxifen resistance in breast cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18700973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/BCR2132

1 reference

Dimensions Publication ID

17 August 2017

0 references

1 reference

17 August 2017

1 reference