Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease (Q36957768)

17 August 2017

Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease (English)

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17 August 2017

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Eric R Secor

1

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17 August 2017

William F Carson

2

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17 August 2017

Michelle M Cloutier

3

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17 August 2017

Linda A Guernsey

4

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17 August 2017

Craig M Schramm

5

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17 August 2017

Carol A Wu

6

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17 August 2017

Roger S Thrall

7

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17 August 2017

1 September 2005

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17 August 2017

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17 August 2017

237

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17 August 2017

1

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17 August 2017

68-75

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Is there a difference between chronic airway inflammation in chronic severe asthma and chronic obstructive pulmonary disease?

17 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects (Review).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Inflammatory events in severe acute asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Insights into the pathogenesis of asthma utilizing murine models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Complementary and alternative interventions in asthma, allergy, and immunology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Patented antiinflammatory plant drug development from traditional medicine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Chronic inhaled ovalbumin exposure induces antigen-dependent but not antigen-specific inhalational tolerance in a murine model of allergic airway disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Regulation of eosinophilopoiesis in a murine model of asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Respiratory and allergic diseases: from upper respiratory tract infections to asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Bromelain reversibly inhibits invasive properties of glioma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Bromelain: biochemistry, pharmacology and medical use.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Bromelain modulates T cell and B cell immune responses in vitro and in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Shifts in lung lymphocyte profiles correlate with the sequential development of acute allergic and chronic tolerant stages in a murine asthma model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Selective modulation of cell adhesion molecules on lymphocytes by bromelain protease 5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Bromelain, biochemical and pharmacological properties

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Phenotypic characterization of T lymphocytes emigrating into lung tissue and the airway lumen after antigen inhalation in sensitized mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

An aqueous Chlorella extract inhibits IL-5 production by mast cells in vitro and reduces ovalbumin-induced eosinophil infiltration in the airway in mice in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Administration of proteolytic enzymes bromelain and trypsin diminish the number of CD4+ cells and the interferon-gamma response in Peyer's patches and spleen in endotoxemic balb/c mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576519

Proinflammatory roles of T-cell receptor (TCR)gammadelta and TCRalphabeta lymphocytes in a murine model of asthma

4 September 2018

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12 December 2020

Activation and transforming growth factor-beta production in eosinophils by hyaluronan

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12 December 2020

Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation

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12 December 2020

Gastrointestinal absorption and antiinflammatory effect of bromelain

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12 December 2020

Induction of adjuvant-independent IgE responses in inbred mice: primary, secondary, and persistent IgE responses to ovalbumin and ovomucoid

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12 December 2020

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia

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12 December 2020

Characterization of a murine model of allergic pulmonary inflammation

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12 December 2020

Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake

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12 December 2020

Requirement for CD44 in activated T cell extravasation into an inflammatory site

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12 December 2020

Prevention of murine EAE by oral hydrolytic enzyme treatment

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12 December 2020

Bromelain, from pineapple stems, proteolytically blocks activation of extracellular regulated kinase-2 in T cells

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12 December 2020

Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients

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12 December 2020

Haemopoietic mechanisms in murine allergic upper and lower airway inflammation

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12 December 2020

10.1016/J.CELLIMM.2005.10.002

Identifiers

DOI

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17 August 2017

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17 August 2017

PubMed publication ID

16337164

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