Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis (Q36964344)

17 August 2017

Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis (English)

1 reference

17 August 2017

Son DNA binding protein

1 reference

GOA release 2020-03-11

Hans Beier Ommen

6

0 references

Peter Hokland

object named as

Peter Hokland

8

0 references

author name string

Eun-Young Ahn

1

1 reference

17 August 2017

Ming Yan

2

1 reference

17 August 2017

Oxana A Malakhova

3

1 reference

17 August 2017

Miao-Chia Lo

4

1 reference

17 August 2017

Anita Boyapati

5

1 reference

17 August 2017

Robert Hines

7

1 reference

17 August 2017

Dong-Er Zhang

9

1 reference

17 August 2017

language of work or name

English

0 references

publication date

24 October 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

1 reference

17 August 2017

105

1 reference

17 August 2017

44

1 reference

17 August 2017

17103-17108

1 reference

Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Proteomic analysis of interchromatin granule clusters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

The dsRNA binding protein family: critical roles, diverse cellular functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

A selection system for human apoptosis inhibitors using yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Decoding of the primary structure of the son3 region in human genome: identification of a new protein with unusual structure and homology with DNA-binding proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Identification of a protein product of a novel human gene SON and the biological effect upon administering a changed form of this gene into mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

A cDNA clone for a novel nuclear protein with DNA binding activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Chromosome translocations: dangerous liaisons revisited.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0802696105

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579385

Cytogenetically cryptic AML1-ETO and CBFbeta-MYH11 gene rearrangements: incidence in 412 cases of acute myeloid leukaemia

20 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18952841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Disease features in acute myeloid leukemia with t(8;21)(q22;q22). Influence of age, secondary karyotype abnormalities, CD19 status, and extramedullary leukemia on survival

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18952841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18952841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0802696105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

18952841

1 reference