beta-cell Regeneration: neogenesis, replication or both? (Q36964497)

17 August 2017

1 reference

title

beta-cell Regeneration: neogenesis, replication or both? (English)

1 reference

17 August 2017

Fred Levine

1

1 reference

PubMed ID

17922102

17 August 2017

Pamela Itkin-Ansari

series ordinal

2

1 reference

17 August 2017

6 October 2007

1 reference

Journal of Molecular Medicine

17 August 2017

1 reference

17 August 2017

86

1 reference

17 August 2017

3

1 reference

17 August 2017

247-258

1 reference

https://scigraph.springernature.com/pub.10.1007/s00109-007-0259-1

17 August 2017

0 references

cites work

Telomerase activity is sufficient to allow transformed cells to escape from crisis

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-007-0259-1

The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

21 January 2018

1 reference

12 December 2020

Effects of Aging on the Regenerative Capacity of the Pancreatic B-Cell of the Rat

1 reference

12 December 2020

c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells

1 reference

12 December 2020

A bipotential precursor population for pancreas and liver within the embryonic endoderm.

1 reference

12 December 2020

Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine

1 reference

12 December 2020

Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo

1 reference

12 December 2020

Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently

1 reference

12 December 2020

In vitro cultivation of human islets from expanded ductal tissue

1 reference

12 December 2020

Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice

1 reference

12 December 2020

Growth Hormone Stimulates Islet B-Cell Replication in Neonatal Rat Pancreatic Monolayer Cultures

1 reference

12 December 2020

Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice

1 reference

12 December 2020

p16INK4a induces an age-dependent decline in islet regenerative potential

1 reference

12 December 2020

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

12 December 2020

Transgenic expression of epidermal growth factor and keratinocyte growth factor in beta-cells results in substantial morphological changes

1 reference

12 December 2020

Histological and Autoradiographic Studies of the Islets of Mice Injected with Insulin Antibody

1 reference

12 December 2020

Exocrine cell transdifferentiation in dexamethasone-treated rat pancreas

1 reference

12 December 2020

The expression of pancreatic endocrine markers in centroacinar cells of the normal and regenerating rat pancreas: their possible transformation to endocrine cells

1 reference

12 December 2020

Mitotic Division in Pancreatic Beta Cells

1 reference

12 December 2020

Glucose-dependent expansion of pancreatic beta-cells by the protein p8 in vitro and in vivo

1 reference

12 December 2020

Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin

1 reference

12 December 2020

Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1

1 reference

12 December 2020

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

12 December 2020

Are there pancreatic progenitor cells from which new islets form after birth?

1 reference

12 December 2020

Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life

1 reference

12 December 2020

Intermediate endocrine-acinar pancreatic cells in duct ligation conditions.

1 reference

12 December 2020

A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development

1 reference

12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

12 December 2020

Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan

1 reference

12 December 2020

Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas.

1 reference

12 December 2020

BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

1 reference

12 December 2020

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.

1 reference

12 December 2020

Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin

1 reference

12 December 2020

Gene therapy for diabetes: strategies for beta-cell modification and replacement

1 reference

12 December 2020

The genetic landscape of type 2 diabetes in mice

1 reference

12 December 2020

A precursor-product relationship exists between oval cells and hepatocytes in rat liver

1 reference

12 December 2020

p57(KIP2) expression in normal islet cells and in hyperinsulinism of infancy.

1 reference

12 December 2020

Growth and regeneration of adult beta cells does not involve specialized progenitors.

1 reference

12 December 2020

The pancreatic ductal epithelium serves as a potential pool of progenitor cells

1 reference

12 December 2020

A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver

1 reference

12 December 2020

Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

1 reference

12 December 2020

The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

1 reference

12 December 2020

Comment on: Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS, Butler PC (2006) direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes. Diabetologia 49:1838-1844

1 reference

12 December 2020

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

12 December 2020

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

1 reference

12 December 2020

Gene transfer to human pancreatic endocrine cells using viral vectors

1 reference

12 December 2020

Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression

1 reference

12 December 2020

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

1 reference

12 December 2020

Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice

1 reference

12 December 2020

Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

1 reference

12 December 2020

Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model

1 reference

12 December 2020

Growth factor/matrix-induced proliferation of human adult beta-cells

1 reference

12 December 2020

Growth factors and beta cell replication.

1 reference

12 December 2020

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

1 reference

12 December 2020

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans.

1 reference

12 December 2020

Diabetes, a New Mutation in the Mouse

1 reference

12 December 2020

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

1 reference

12 December 2020

Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells

1 reference

12 December 2020

Ductal cyst formation in collagen-embedded adult human islet preparations. A means to the reproduction of nesidioblastosis in vitro

1 reference

12 December 2020

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

12 December 2020

Timing and expression pattern of carbonic anhydrase II in pancreas

1 reference

12 December 2020

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

12 December 2020

An immunocytochemical profile of the endocrine pancreas using an occlusive duct ligation model.

1 reference

12 December 2020

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c

1 reference

12 December 2020

Age, body mass index and Type 2 diabetes-associations modified by ethnicity

1 reference

12 December 2020

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

1 reference

12 December 2020

Impaired beta-cell function and insulin sensitivity in Japanese subjects with normal glucose tolerance

1 reference

12 December 2020

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

12 December 2020

In vivo differentiation of rat liver oval cells into hepatocytes.

1 reference

12 December 2020

Acid beta-galactosidase: a developmentally regulated marker of endocrine cell precursors in the human fetal pancreas

1 reference

12 December 2020

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

1 reference

12 December 2020

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

1 reference

12 December 2020

Regulation of islet beta-cell proliferation by prolactin in rat islets

1 reference

12 December 2020

PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line

1 reference

12 December 2020

Pancreatic beta cell proliferation in rabbits demonstrated by bromodeoxyuridine labeling

1 reference

12 December 2020

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1 reference

12 December 2020

Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer

1 reference

12 December 2020

Formation of insulin-positive cells in implants of human pancreatic duct cell preparations from young donors.

1 reference

12 December 2020

Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice

1 reference

12 December 2020

Sustained proliferation of PDX-1+ cells derived from human islets

1 reference

12 December 2020

Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro

1 reference

12 December 2020

All beta cells contribute equally to islet growth and maintenance

1 reference

12 December 2020

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

1 reference

12 December 2020

Adult human pancreatic duct and islet cells exhibit similarities in expression and differences in phosphorylation and complex formation of the homeodomain protein Ipf-1

1 reference

12 December 2020

Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes

1 reference

12 December 2020

Induction of islet cell neogenesis in the adult pancreas: the partial duct obstruction model

1 reference

12 December 2020

A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

1 reference

12 December 2020

Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas

1 reference

12 December 2020

Adaptation of islets of Langerhans to pregnancy: beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones

1 reference

12 December 2020

Mechanisms of liver regeneration and their clinical implications

1 reference

12 December 2020

Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4.

1 reference

12 December 2020

Very slow turnover of beta-cells in aged adult mice

1 reference

12 December 2020

Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates

1 reference

12 December 2020

No pancreatic endocrine stem cells?

1 reference

12 December 2020

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

12 December 2020

Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro

1 reference

12 December 2020

Molecular etiologies of MODY and other early-onset forms of diabetes

1 reference

12 December 2020

Molecular control of cell cycle progression in the pancreatic beta-cell

1 reference

12 December 2020

In Vivo Cell Transformation: Neogenesis of Beta Cells from Pancreatic Ductal Cells

1 reference

12 December 2020

Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets

1 reference

12 December 2020

10.1007/S00109-007-0259-1

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17922102