Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues (Q36964943)

17 August 2017

Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues (English)

1 reference

17 August 2017

1 reference

K M Waldhauser

1

1 reference

17 August 2017

K Brecht

2

1 reference

17 August 2017

S Hebeisen

3

1 reference

17 August 2017

H R Ha

4

1 reference

17 August 2017

D Konrad

5

1 reference

17 August 2017

D Bur

6

1 reference

17 August 2017

S Krähenbühl

7

1 reference

17 August 2017

language of work or name

English

0 references

publication date

7 July 2008

1 reference

British Journal of Pharmacology

17 August 2017

1 reference

17 August 2017

155

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17 August 2017

4

1 reference

17 August 2017

585-595

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Lysosomal sequestration of amine-containing drugs: analysis and therapeutic implications

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Toxicity of statins on rat skeletal muscle mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Mechanisms of benzarone and benzbromarone-induced hepatic toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Identification and quantitation of novel metabolites of amiodarone in plasma of treated patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Energetic optimization of ion conduction rate by the K+ selectivity filter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Antiarrhythmic actions of amiodarone: a profile of a paradoxical agent

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Amiodarone pulmonary toxicity. Recognition and pathogenesis (Part 2).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Amiodarone pulmonary toxicity. Recognition and pathogenesis (Part I).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Amiodarone-induced liver toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Histopathologic analysis of suspected amiodarone hepatotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Amiodarone pulmonary toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Drug-induced phospholipidoses. II. Tissue distribution of the amphiphilic drug chlorphentermine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Effects of amiodarone on thyroid function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Interaction of the antiarrhythmic agents SR 33589 and amiodarone with the beta-adrenoceptor and adenylate cyclase in rat heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

In vitro inhibition of lysosomal phospholipase A1 of rat lung by amiodarone and desethylamiodarone

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Guide to Receptors and Channels (GRAC), 3rd edition

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Effects of amiodarone and dronedarone on voltage-dependent sodium current in human cardiomyocytes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Toxicity of amiodarone and amiodarone analogues on isolated rat liver mitochondria

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Inhibition of L-type Ca2+ channel current in Xenopus oocytes by amiodarone

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Interaction between amiodarone and lidocaine.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2579668

Synthesis and cytotoxicity properties of amiodarone analogues

4 September 2018

1 reference

12 December 2020

Structure-effect relationships of amiodarone analogues on the inhibition of thyroxine deiodination

1 reference

12 December 2020

Mitochondrial diseases represent a risk factor for valproate-induced fulminant liver failure

1 reference

12 December 2020

Identification and measurement of desethylamiodarone in blood plasma specimens from amiodarone-treated patients

1 reference

12 December 2020

Role of phospholipase A inhibition in amiodarone pulmonary toxicity in rats

1 reference

12 December 2020

Determination of hydrophobic parameters by reversed-phase liquid chromatography: theory, experimental techniques, and application in studies on quantitative structure-activity relationships

1 reference

12 December 2020

1 reference

12 December 2020

Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients

1 reference

12 December 2020

Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice

1 reference

12 December 2020

Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II

1 reference

12 December 2020

Amiodarone-induced lymphocyte toxicity and mitochondrial function

1 reference

12 December 2020

Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB

1 reference

12 December 2020

Amiodarone-induced pulmonary toxicity. Predisposing factors, clinical symptoms and treatment

1 reference

12 December 2020

Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJP.2008.287

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

18604229

1 reference