Novel methods for detecting epistasis in pharmacogenomics studies (Q36966054)

17 August 2017

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title

Novel methods for detecting epistasis in pharmacogenomics studies (English)

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17 August 2017

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Marylyn D Ritchie

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PubMed ID

17924838

17 August 2017

Alison Motsinger-Reif

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1

object named as

Alison A Motsinger

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17 August 2017

David M Reif

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17 August 2017

1 September 2007

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17 August 2017

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17 August 2017

8

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9

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17 August 2017

1229-1241

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The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

17 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A perspective on epistasis: limits of models displaying no main effect

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

New strategies for identifying gene-gene interactions in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Dynamic relationships between the genome and exposures to environments as causes of common human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Genetics, statistics and human disease: analytical retooling for complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Combinatorial pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Computational analysis of gene-gene interactions using multifactor dimensionality reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Machine learning for detecting gene-gene interactions: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Detecting epistatic interactions contributing to quantitative traits

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A novel method to identify gene-gene effects in nuclear families: the MDR-PDT.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction model on childhood allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

21 January 2018

Grammatical evolution

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Two-stage two-locus models in genome-wide association

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Trimming, weighting, and grouping SNPs in human case-control association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A testing framework for identifying susceptibility genes in the presence of epistasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A note on exact tests of Hardy-Weinberg equilibrium

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Patterns of linkage disequilibrium in the human genome

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Linkage disequilibrium in humans: models and data

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

SNP and haplotype variation in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Evaluating bias due to population stratification in epidemiologic studies of gene-gene or gene-environment interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Genomic control for association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Content-rich biological network constructed by mining PubMed abstracts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

KGraph: a system for visualizing and evaluating complex genetic associations.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

A combinatorial searching method for detecting a set of interacting loci associated with complex traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Haplotype interaction analysis of unlinked regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Tree-structured supervised learning and the genetics of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Test for interaction between two unlinked loci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Multivariate Adaptive Regression Splines

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Learning Petri net models of non-linear gene interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

On lines and planes of closest fit to systems of points in space

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Candidate gene association analysis for a quantitative trait, using parent-offspring trios.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Two-level Haseman-Elston regression for general pedigree data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

The Challenges of Whole-Genome Approaches to Common Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

MDR and PRP: A Comparison of Methods for High-Order Genotype-Phenotype Associations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Family-based association analysis with ordered categorical phenotypes, covariates and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Mixed modelling to characterize genotype–phenotype associations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.9.1229

10.2217/14622416.8.9.1229

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17924838