Expanding role of lipid II as a target for lantibiotics (Q36967247)

17 August 2017

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title

Expanding role of lipid II as a target for lantibiotics (English)

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17 August 2017

2

Eefjan Breukink

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17 August 2017

Nathaniel I Martin

1

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17 August 2017

1 October 2007

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17 August 2017

13

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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17 August 2017

2

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17 August 2017

5

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17 August 2017

513-525

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

17 August 2017

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https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Isolation and separation of the glycan strands from murein of Escherichia coli by reversed-phase high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Recent advances in the formation of the bacterial peptidoglycan monomer unit

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Substrate analogues to study cell-wall biosynthesis and its inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Transmembrane transport of peptidoglycan precursors across model and bacterial membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Resistance of Gram-positive bacteria to nisin is not determined by lipid II levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Paramagnetic isoprenoid carrier lipids. 1. Chemical synthesis and incorporation into model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

An oxidative phenol coupling reaction catalyzed by oxyB, a cytochrome P450 from the vancomycin-producing microorganism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Oxidative phenol coupling reactions catalyzed by OxyB: a cytochrome P450 from the vancomycin producing organism. implications for vancomycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Specificity of combination between mucopeptide precursors and vancomycin or ristocetin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structure of vancomycin and a vancomycin/D-Ala-D-Ala complex in solution

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Getting closer to the real bacterial cell wall target: biomolecular interactions of water-soluble lipid II with glycopeptide antibiotics

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Genetics and mechanisms of glycopeptide resistance in enterococci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

The emergence of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Recently approved and investigational antibiotics for treatment of severe infections caused by Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Resistance to vancomycin and teicoplanin: an emerging clinical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Origin, structure, and activity in vitro and in vivo of dalbavancin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Oritavancin: a new avenue for resistant Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Chemistry and biology of the ramoplanin family of peptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Chemistry and biology of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Rethinking ramoplanin: the role of substrate binding in inhibition of peptidoglycan biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Mechanism of action of the mannopeptimycins, a novel class of glycopeptide antibiotics active against vancomycin-resistant gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Katanosin B and plusbacin A(3), inhibitors of peptidoglycan synthesis in methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Isolation and characterization of katanosins A and B

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lipid II as a target for antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lantibiotics produced by lactic acid bacteria: structure, function and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

MICs of mutacin B-Ny266, nisin A, vancomycin, and oxacillin against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Biosynthesis and mode of action of lantibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Bacterial lantibiotics: strategies to improve therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lantibiotic biosynthesis: interactions between prelacticin 481 and its putative modification enzyme, LctM

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

The biology of lantibiotics from the lacticin 481 group is coming of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Additional antibiotic inhibitors of peptidoglycan synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

In vitro pore-forming activity of the lantibiotic nisin. Role of protonmotive force and lipid composition.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Interaction of the lantibiotic nisin with membranes revealed by fluorescence quenching of an introduced tryptophan.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

The orientation of nisin in membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Voltage-dependent depolarization of bacterial membranes and artificial lipid bilayers by the peptide antibiotic nisin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lipid II induces a transmembrane orientation of the pore-forming peptide lantibiotic nisin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lipid II-mediated pore formation by the peptide antibiotic nisin: a black lipid membrane study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Targeting extracellular pyrophosphates underpins the high selectivity of nisin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Assembly and stability of nisin-lipid II pores

21 January 2018

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https://api.crossref.org/works/10.2217%2F17460913.2.5.513

The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Two-peptide bacteriocins produced by lactic acid bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Streptococcus rattus strain BHT produces both a class I two-component lantibiotic and a class II bacteriocin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Nisin resistance of Streptococcus bovis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

The Bacillus subtilis extracytoplasmic-function sigmaX factor regulates modification of the cell envelope and resistance to cationic antimicrobial peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

Antibacterial efficacy of nisin against multidrug-resistant Gram- positive pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460913.2.5.513

21 January 2018

Identifiers

DOI

10.2217/17460913.2.5.513

1 reference

17 August 2017

1 reference

PubMed ID

17927474