From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. (Q36974036)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19018291%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond (English)

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17 January 2020

1 reference

5

Fazlul H Sarkar

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17 January 2020

author name string

Subhash Padhye

1

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17 January 2020

Sanjeev Banerjee

2

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17 January 2020

Aamir Ahmad

3

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17 January 2020

Ramzi Mohammad

4

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17 January 2020

publication date

1 January 2008

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17 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19018291%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

6

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17 January 2020

issue

b

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17 January 2020

page(s)

495-510

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Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells

17 January 2020

cites work

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Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.

29 September 2017

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Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models

29 September 2017

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Androgen receptor and E2F-1 targeted thymoquinone therapy for hormone-refractory prostate cancer

29 September 2017

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Thymoquinone suppressses in vitro production of IL-5 and IL-13 by mast cells in response to lipopolysaccharide stimulation

29 September 2017

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Anti-tumor properties of blackseed (Nigella sativa L.) extracts

29 September 2017

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Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), thymoquinone (TQ), and selenium (SE).

29 September 2017

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A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells

29 September 2017

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LNCaP cells exposed to ceramic drug delivery treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid.

29 September 2017

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Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation

29 September 2017

1 reference

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Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells

29 September 2017

1 reference

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The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo

29 September 2017

1 reference

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Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus

29 September 2017

1 reference

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Evaluation of bioflavonoids as potential chemotherapeutic agents.

29 September 2017

1 reference

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Effects of (-)epigallocatechin gallate and thymoquinone on proliferation of a PANC-1 cell line in culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The effect of conventional and sustained delivery of thymoquinone and levodopa on SH-SY5Y human neuroblastoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Effects of thymoquinone, lycopene, and selenomethione in the presence of estrogen on the viability of SiHa cells in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Modes of action of alpha-hederin and thymoquinone, active constituents of Nigella sativa, against HEp-2 cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Immunomodulatory and therapeutic properties of the Nigella sativa L. seed.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The effects of isolated antioxidants from black seed on the cellular metabolism of A549 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Crystal structure determination of thymoquinone by high-resolution X-ray powder diffraction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Helicobacter infection, chronic inflammation, and the development of malignancy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention.

29 September 2017

1 reference

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Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies

29 September 2017

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Dietary antioxidants and human cancer

29 September 2017

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Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.

29 September 2017

1 reference

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Role of the RB tumor suppressor in cancer.

29 September 2017

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In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone.

29 September 2017

1 reference

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The influence of thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats

29 September 2017

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Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone

29 September 2017

1 reference

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

29 September 2017

1 reference

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Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity

29 September 2017

1 reference

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Pericholangitis and sclerosing cholangitis are risk factors for dysplasia and cancer in ulcerative colitis

29 September 2017

1 reference

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WAF1, a potential mediator of p53 tumor suppression

29 September 2017

1 reference

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Cell cycle control and cancer

29 September 2017

1 reference

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Checkpoints: controls that ensure the order of cell cycle events

29 September 2017

1 reference

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Ulcerative colitis and colorectal cancer. A population-based study

29 September 2017

1 reference

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

29 September 2017

1 reference

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages

27 June 2018

1 reference

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Nigella sativa oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats

27 June 2018

1 reference

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Hepatoprotective activity of thymoquinone in isolated rat hepatocytes.

27 June 2018

1 reference

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Cancer in universal and left-sided ulcerative colitis: factors determining risk

27 June 2018

1 reference

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Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions

27 June 2018

1 reference

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n-Hexane toxicity in Jurkat T-cells is mediated by reactive oxygen species

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone protects renal tubular cells against tubular injury

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Anticlastogenic activity of thymoquinone against benzo(a)pyrene in mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of thymoquinone.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone inhibits the activation of NF-kappaB in the brain and spinal cord of experimental autoimmune encephalomyelitis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Comparison of the amelioration effects of two enzyme inducers on the inflammatory process of experimental allergic encephalitis (EAE) using immunohistochemical technique.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Relation between deranged antioxidant system and cervical neoplasia

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

A simple differential pulse polarographic method for the determination of thymoquinone in black seed oil.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone is a potent superoxide anion scavenger

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Thymoquinone protects against experimental colitis in rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Improvement of experimental allergic encephalomyelitis (EAE) by thymoquinone; an oxidative stress inhibitor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The effect of thymol and its derivatives on reactions generating reactive oxygen species.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Nonenzymatic reduction of thymoquinone in physiological conditions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583426

Allergic contact dermatitis from black cumin (Nigella sativa) oil-containing ointment

4 December 2018

1 reference

12 December 2020

Thymoquinone supplementation prevents the development of gentamicin-induced acute renal toxicity in rats

1 reference

12 December 2020

Effects of the volatile oil of Nigella sativa seeds on the uterine smooth muscle of rat and guinea pig

1 reference

12 December 2020

High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.).

1 reference

12 December 2020

Effects of Nigella sativa and its major constituent, thymoquinone on sciatic nerves in experimental diabetic neuropathy

1 reference

12 December 2020

Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism

1 reference

12 December 2020

Inhibition of histamine release from mast cells by nigellone

1 reference

12 December 2020

Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis

1 reference

12 December 2020

[Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]

1 reference

12 December 2020

Colorectal cancer in inflammatory bowel disease

1 reference

12 December 2020

Risk and natural history of colonic neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis

1 reference

12 December 2020

Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation

1 reference

12 December 2020

Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19018291%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference