The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds (Q36977156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

main subject

antimicrobial peptide

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Monique van Hoek

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Allen J Duplantier

series ordinal

1

1 reference

17 August 2017

3 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

published in

Frontiers in Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

A comprehensive summary of LL-37, the factotum human cathelicidin peptide.

4 March 2020

cites work

1 reference

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Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37.

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The human cathelicidin hCAP18/LL-37: a multifunctional peptide involved in mycobacterial infections

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Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery

29 September 2017

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The chemistry and biology of LL-37

29 September 2017

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Anti-biofilm strategies and the need for innovations in wound care.

29 September 2017

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29 September 2017

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Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils

29 September 2017

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Regular debridement is the main tool for maintaining a healthy wound bed in most chronic wounds

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The roles of cathelicidin LL-37 in immune defences and novel clinical applications

29 September 2017

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29 September 2017

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29 September 2017

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The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.

29 September 2017

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29 September 2017

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29 September 2017

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Human host defense peptide LL-37 prevents bacterial biofilm formation

29 September 2017

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29 September 2017

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NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles

29 September 2017

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Survey of bacterial diversity in chronic wounds using pyrosequencing, DGGE, and full ribosome shotgun sequencing

29 September 2017

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29 September 2017

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Human cathelicidin CAP18/LL-37 changes mast cell function toward innate immunity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure

29 September 2017

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The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes

29 September 2017

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Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

29 September 2017

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Antimicrobial and Protease Inhibitory Functions of the Human Cathelicidin (hCAP18/LL-37) Prosequence

29 September 2017

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Mechanisms of antimicrobial peptide action and resistance

29 September 2017

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Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37.

29 September 2017

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29 September 2017

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29 September 2017

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Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis

29 September 2017

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Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells

29 September 2017

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Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

29 September 2017

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Induction of direct antimicrobial activity through mammalian toll-like receptors

29 September 2017

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LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

29 September 2017

1 reference

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Core structure of the outer membrane lipoprotein from Escherichia coli at 1.9 A resolution

29 September 2017

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Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein

29 September 2017

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29 September 2017

1 reference

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29 September 2017

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27 June 2018

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Signaling pathways mediating chemokine induction in keratinocytes by cathelicidin LL-37 and flagellin.

27 June 2018

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Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin

4 September 2018

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4 September 2018

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Stability of the cathelicidin peptide LL-37 in a non-healing wound environment.

4 September 2018

1 reference

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Combined treatment of Pseudomonas aeruginosa biofilm with lactoferrin and xylitol inhibits the ability of bacteria to respond to damage resulting from lactoferrin iron chelation.

4 September 2018

1 reference

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4 September 2018

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Diabetic foot infections: A need for innovative assessments.

4 September 2018

1 reference

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Effects of biofilm treatments on the multi-species Lubbock chronic wound biofilm model

4 September 2018

1 reference

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The cathelicidin LL-37 activates human mast cells and is degraded by mast cell tryptase: counter-regulation by CXCL4.

4 September 2018

1 reference

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In vitro susceptibility of established biofilms composed of a clinical wound isolate of Pseudomonas aeruginosa treated with lactoferrin and xylitol

4 September 2018

1 reference

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APD2: the updated antimicrobial peptide database and its application in peptide design

4 September 2018

1 reference

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The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37.

4 September 2018

1 reference

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A study of biofilm-based wound management in subjects with critical limb ischaemia.

4 September 2018

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Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening

4 September 2018

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Biofilms in chronic wounds

4 September 2018

1 reference

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An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

Glycosaminoglycans inhibit the antibacterial activity of LL-37 in biological fluids

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

Human beta-defensin-3 promotes wound healing in infected diabetic wounds

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699762

Biofilm maturity studies indicate sharp debridement opens a time-dependent therapeutic window

4 December 2018

1 reference

12 December 2020

Inhibitory effects of lactoferrin on biofilm formation in clinical isolates of Pseudomonas aeruginosa

1 reference

12 December 2020

The role of salivary histatin and the human cathelicidin LL-37 in wound healing and innate immunity

1 reference

12 December 2020

Multiple trauma induces serum production of host defence peptides

1 reference

12 December 2020

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

1 reference

12 December 2020

Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37

1 reference

12 December 2020

Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes

1 reference

12 December 2020

An ELISA for hCAP-18, the cathelicidin present in human neutrophils and plasma

1 reference

12 December 2020

Staphylococcal biofilms impair wound healing by delaying reepithelialization in a murine cutaneous wound model

1 reference

12 December 2020

Induction of keratinocyte migration via transactivation of the epidermal growth factor receptor by the antimicrobial peptide LL-37

1 reference

12 December 2020

Outcomes of bacteremia in burn patients involved in combat operations overseas

1 reference

12 December 2020

Improvement in burn wound infection and survival with antimicrobial peptide D2A21 (Demegel)

1 reference

12 December 2020

Chronic wounds and the medical biofilm paradigm

1 reference

12 December 2020

Molecular Mechanisms of RIP, an Effective Inhibitor of Chronic Infections

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2013.00143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

23840194

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840194%20AND%20SRC:MED&resulttype=core&format=json