Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load. (Q36980296)

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7 January 2020

title

Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load (English)

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6

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author name string

Jaime Desantiago

1

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7 January 2020

Xun Ai

2

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Mohammed Islam

3

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Georgia Acuna

4

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Mark T Ziolo

5

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Steven M Pogwizd

7

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publication date

8 May 2008

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volume

102

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issue

11

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7 January 2020

page(s)

1389-1397

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Caveolae modulate excitation-contraction coupling and beta2-adrenergic signalling in adult rat ventricular myocytes

7 January 2020

cites work

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Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial

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The molecular basis for distinct beta-adrenergic receptor subtype actions in cardiomyocytes

29 September 2017

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Recent advances in cardiac beta(2)-adrenergic signal transduction

29 September 2017

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Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

29 September 2017

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Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.

29 September 2017

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Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

4 September 2018

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Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes

4 September 2018

1 reference

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Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts

4 September 2018

1 reference

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Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent G(s) signaling during beta2-adrenergic stimulation

4 September 2018

1 reference

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Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness

4 September 2018

1 reference

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Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

4 September 2018

1 reference

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Coexistence of beta 1- and beta 2-adrenoceptors in the rabbit heart: quantitative analysis of the regional distribution by (-)-3H-dihydroalprenolol binding

4 September 2018

1 reference

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Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure

4 September 2018

1 reference

12 December 2020

Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance

1 reference

12 December 2020

Laminin binding to beta1-integrins selectively alters beta1- and beta2-adrenoceptor signalling in cat atrial myocytes

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12 December 2020

Sudden unexpected death in patients with congestive heart failure: a second frontier

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12 December 2020

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

1 reference

12 December 2020

Beta 2-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation

1 reference

12 December 2020

Nonreentrant mechanisms underlying spontaneous ventricular arrhythmias in a model of nonischemic heart failure in rabbits

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12 December 2020

Response of failing canine and human heart cells to beta 2-adrenergic stimulation

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12 December 2020

Steady-state twitch Ca2+ fluxes and cytosolic Ca2+ buffering in rabbit ventricular myocytes

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12 December 2020

Beta2-adrenergic receptor antagonists protect against ventricular fibrillation: in vivo and in vitro evidence for enhanced sensitivity to beta2-adrenergic stimulation in animals susceptible to sudden death

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12 December 2020

Do beta 2-adrenergic receptors modulate Ca2+ in adult rat ventricular myocytes?

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12 December 2020

Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy

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12 December 2020

Activation of beta2-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure

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12 December 2020

beta2-adrenergic cAMP signaling is uncoupled from phosphorylation of cytoplasmic proteins in canine heart

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12 December 2020

Left ventricular function and beta-adrenoceptors in rabbit failing heart

1 reference

12 December 2020

Beta 1-adrenoceptor stimulation and beta 2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells

1 reference

12 December 2020

Coexistence of functioning beta 1- and beta 2-adrenoceptors in single myocytes from human ventricle

1 reference

12 December 2020

10.1161/CIRCRESAHA.107.169011

Identifiers

DOI

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