Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection. (Q36980449)

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9 January 2020

review article

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title

Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection (English)

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9 January 2020

3

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J E Doe

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Olavi Pelkonen

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9 January 2020

1

Lorenz R Rhomberg

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9 January 2020

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James Bus

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9 January 2020

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Karl Baetcke

2

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Samuel Cohen

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Rory Conolly

6

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Rakesh Dixit

7

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Karen Ekelman

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Penny Fenner-Crisp

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Paul Harvey

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Dale Hattis

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Abigail Jacobs

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David Jacobson-Kram

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Tom Lewandowski

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Robert Liteplo

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Jerry Rice

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Diana Somers

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Angelo Turturro

20

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Webster West

21

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Stephen Olin

22

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English

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publication date

1 January 2007

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Critical Reviews in Toxicology

9 January 2020

published in

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volume

37

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9 January 2020

page(s)

729-837

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issue

9

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Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies

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21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Pharmacogenetics and folate metabolism -- a promising direction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Is p53 haploinsufficient for tumor suppression? Implications for the p53+/- mouse model in carcinogenicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Nucleic acid based techniques for the detection of rare cancer cells in clinical samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Dose-dependent fate of vinyl chloride and its possible relationship to oncogenicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Molecular damage in the bronchial epithelium of current and former smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Analysis for loss of heterozygosity (LOH) of p53 allele in tumors derived from p53+/- and CD-1 mice following repeated subcutaneous injections of solutions containing antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

A Probabilistic Framework for the Reference Dose (Probabilistic RfD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

Anatomical site-specific response to DNA damage is related to later tumor development in the rat azoxymethane colon carcinogenesis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701524949

10.1080/10408440701524949

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957539%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference