In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice (Q36982753)

17 August 2017

In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice (English)

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17 August 2017

10

George S Eisenbarth

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17 August 2017

4

Ronald F Parsons

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17 August 2017

13

Hooman Noorchashm

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17 August 2017

Ghazal Zekavat

1

1 reference

17 August 2017

Susan Y Rostami

2

1 reference

17 August 2017

Armen Badkerhanian

3

1 reference

17 August 2017

Brigitte Koeberlein

5

1 reference

17 August 2017

Ming Yu

6

1 reference

17 August 2017

Christopher D Ward

7

1 reference

17 August 2017

Thi-Sau Migone

8

1 reference

17 August 2017

Liping Yu

9

1 reference

17 August 2017

Michael P Cancro

11

1 reference

17 August 2017

Ali Naji

12

1 reference

17 August 2017

language of work or name

English

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publication date

1 December 2008

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17 August 2017

Journal of Immunology

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17 August 2017

181

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17 August 2017

11

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17 August 2017

8133-8144

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Insulin as an autoantigen in NOD/human diabetes

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Role of autoantibodies in type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Space, selection, and surveillance: setting boundaries with BLyS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

The BLyS family of ligands and receptors: an archetype for niche-specific homeostatic regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Generation and characterization of LymphoStat‐B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

BAFF: a fundamental survival factor for B cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Suppressor T cells--they're back and critical for regulation of autoimmunity!

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte-deficient A/WySnJ mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Cutting edge: impaired transitional B cell production and selection in the nonobese diabetic mouse.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586964

'The honeymoon phase' in children with type 1 diabetes mellitus: frequency, duration, and influential factors

4 September 2018

1 reference

12 December 2020

Belimumab Human Genome Sciences/Cambridge Antibody Technology/GlaxoSmithKline

1 reference

12 December 2020

Generation of peripheral B cells occurs via two spatially and temporally distinct pathways

1 reference

12 December 2020

TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells

1 reference

12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

1 reference

12 December 2020

Gateways to clinical trials

1 reference

12 December 2020

Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice

1 reference

12 December 2020

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice

1 reference

12 December 2020

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

1 reference

12 December 2020

Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers

1 reference

12 December 2020

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

1 reference

12 December 2020

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice

1 reference

12 December 2020

Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice

1 reference

12 December 2020

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice

1 reference

12 December 2020

Contribution of the Innate Immune System to Autoimmune Diabetes: A Role for the CR1/CR2 Complement Receptors

1 reference

12 December 2020

The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11

1 reference

12 December 2020

Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse

1 reference

12 December 2020

10.4049/JIMMUNOL.181.11.8133

Identifiers

DOI

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17 August 2017

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17 August 2017

1 reference